SynthesisSurgical endoscopy2022
Risk of recurrence after local resection of T1 rectal cancer: a meta-analysis with meta-regression.
Synthesis in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Pathologic upstaging after definitive transanal endoscopic surgery for cT1N0M0 rectal cancer: patterns of care and survival.Surgical endoscopy · 2026Article
- Transanal endoscopic microsurgery was associated with higher recurrence rate in both low- and high-risk T1 rectal cancer compared to surgical resection.Surgical endoscopy · 2026Article
- Long-term outcomes of pT1 rectal cancer after transanal endoscopic surgery: again, a word of caution on high local recurrence - a cohort study.International journal of colorectal disease · 2026Observational
- [Technical advances in endoscopic resection : Potential, limits and the necessary interdisciplinary dialogue with surgery].Innere Medizin (Heidelberg, Germany) · 2026Review
- Modern Approaches to Rectal Cancer: Integrating Endoscopic, Surgical, and Oncological Care.Cancers · 2025Review
- Sphincter-preserving surgical techniques in low rectal cancer management: A systematic review of contemporary evidence.World journal of gastrointestinal surgery · 2025Review
- Endoscopic surveillance for colorectal cancer and its precursor lesions in Lynch syndrome; time for some policy shifts?Hereditary cancer in clinical practice · 2025Article
- Minimally invasive transanal excision over conventional transanal excision: pursuing the perfect removal of early rectal cancer.Annals of coloproctology · 2025Article
- Is tumour location a dominant risk factor of recurrence in early rectal cancer?Surgical endoscopy · 2025Article
- Complete resection of recurrent anal canal cancer using endoscopic submucosal dissection and transanal resection: A case report.World journal of gastrointestinal endoscopy · 2025Article
- Local Recurrence of Premalignant and Early Malignant Rectal Polyps Treated by TEM-A Single-Center Experience.Journal of clinical medicine · 2024Article
- Local excision for middle-low rectal cancer after neoadjuvant chemoradiation: A retrospective study from a single tertiary center.World journal of gastrointestinal oncology · 2024Article
- Article
- Risk Factors for Rectal Cancer Recurrence after Local Excision of T1 Lesions from a Decade-Long Multicenter Retrospective Study.Journal of clinical medicine · 2024Article
- T1 colorectal cancer management in the era of minimally invasive endoscopic resection.World journal of gastrointestinal oncology · 2024Article
- Article
- Treatment Options for Distal Rectal Cancer in the Era of Organ Preservation.Current treatment options in oncology · 2024Review
- Patient educational videos on T1 colorectal cancer.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2023Article
- Outcome of Completion Surgery after Endoscopic Submucosal Dissection in Early-Stage Colorectal Cancer Patients.Cancers · 2023Article
- Colorectal polyps: Targets for fluorescence-guided endoscopy to detect high-grade dysplasia and T1 colorectal cancer.United European gastroenterology journal · 2023Article
Corrections and comments
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Authors and funding
19 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundT1 rectal cancer (RC) patients are increasingly being treated by local resection alone but uniform surveillance strategies thereafter are lacking. To determine whether different local resection techniques influence the risk of recurrence and cancer-related mortality, a meta-analysis was performed.
methodsA systematic search was conducted for T1RC patients treated with local surgical resection. The primary outcome was the risk of RC recurrence and RC-related mortality. Pooled estimates were calculated using mixed-effect logistic regression. We also systematically searched and evaluated endoscopically treated T1RC patients in a similar manner.
resultsIn 2585 unique T1RC patients (86 studies) undergoing local surgical resection, the overall pooled cumulative incidence of recurrence was 9.1% (302 events, 95% CI 7.3-11.4%; I
conclusionsPatients with T1 rectal cancer may have a significantly lower recurrence risk after TEM/TAMIS compared to other local surgical resection techniques. After TEM/TAMIS and endoscopic resection the recurrence risk, cancer-related mortality and cancer-related mortality among patients with recurrence were comparable. Recurrence was mainly dependent on histological risk status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.