Evidence map›Paper›PMID 35773569›Full record

ArticleOphthalmology and therapy2022

CO

Min Chen, Naiji Yu, Chunlian Huang, Qi Zhang, Xin Liu, Kaijun Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ophthalmology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Management and outcomes of primary open-angle glaucoma.Journal of family medicine and primary care · 2026
    Review
  2. An overview and update of COExperimental and therapeutic medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Min Chen *Eye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, 310009, Zhejiang, China.ORCID http://orcid.org/0000-0003-0460-8403
Naiji Yu *Eye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, 310009, Zhejiang, China.ORCID http://orcid.org/0000-0003-2301-7107
Chunlian HuangEye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, 310009, Zhejiang, China.ORCID http://orcid.org/0000-0001-7661-0962
Qi ZhangEye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, 310009, Zhejiang, China.ORCID http://orcid.org/0000-0003-3443-7326
Xin LiuEye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, 310009, Zhejiang, China.ORCID http://orcid.org/0000-0002-2561-9809
Kaijun WangEye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, No. 1 Xihu Boulevard, Hangzhou, 310009, Zhejiang, China. ze_wkj@zju.edu.cn.ORCID http://orcid.org/0000-0001-6961-3655
Second Affiliated Hospital of Zhejiang University · CNTaizhou Central Hospital · CNZhejiang Technical Institute of Economics · CN

Funding

National Natural Science Foundation of China No. 82171045Zhejiang Province Public Welfare Technology Application Research Project No. LGF20H120003
6 · The paper itself

Abstract

introductionTo compare 1-year outcomes of CO

methodsThis was a prospective, comparative, case series study. A total of 46 eyes with POAG underwent CLASS or CLASS + Phaco were followed up for 1 year. The primary outcomes included changes in intraocular pressure (IOP), medication and best corrected visual acuity (BCVA). The secondary outcomes were success rate, functional bleb, postoperative laser intervention and complications.

resultsCLASS alone resulted in a greater IOP reduction compared with CLASS + Phaco. BCVA improved remarkably in CLASS + Phaco group, but there was no difference in BCVA before and after CLASS. The number of antiglaucoma medications significantly decreased at 12 months postoperatively in both groups. Functional blebs were more commonly seen in the CLASS than combination group. The overall success rate was higher in the CLASS than CLASS + Phaco group at 1 year after surgery. The incidence of peripheral anterior synechiae (PAS) in CLASS + Phaco group was significantly lower than that of CLASS alone.

conclusionCLASS alone achieved a greater IOP reduction, more common functional bleb formation and a higher success rate compared to CLASS combined with Phaco, while combination surgery yielded a better BCVA improvement and a lower PAS incidence than CLASS alone. Both surgical strategies have favorable safety and efficacy among POAG patients. Combined surgery could be a viable option for patients with co-existing POAG and cataract.

Indexed as

CataractCO2 laserDeep sclerectomyIntraocular pressurePhacoemulsificationPrimary open-angle glaucoma

Identifiers

PMID35773569
PMCPMC9437161
OpenAlexW4283716237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.