Evidence map›Paper›PMID 35773531›Full record

ArticleInternational orthopaedics2022

Incidence and management of surgical site infection in the cervical spine following a transoral approach.

Hu Chen, Changrong Zhu, Honglei Yi, Hao Sun, Xiangyang Ma, Jianhua Wang, Kai Zhang, Fuzhi Ai, Zenghui Wu, Qingshui Yin and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Timing of cervical spine fixation and its impact on postoperative outcomes: a retrospective analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Posterior intra-articular distraction technique to treat pediatric atlantoaxial instability.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  9. Article
  10. Incidences, causes and risk factors of unplanned reoperation within 30 days of craniovertebral junction surgery: a single-center experience.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hu ChenThe First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Changrong ZhuThe First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Honglei YiThe First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Hao SunDepartment of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China.
Xiangyang MaThe First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Jianhua WangThe First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Kai ZhangDepartment of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China.
Fuzhi AiDepartment of Orthopedic, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Zenghui WuDepartment of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China.
Qingshui YinDepartment of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China.
Qiang TuThe First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. tuqiang@126.com.
Hong XiaThe First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. gzxiahong2@126.com.ORCID http://orcid.org/0000-0003-3651-8410
Southern Medical University · CNGeneral Hospital of Guangzhou Military Command · CNSun Yat-sen University · CN

Funding

Army Logistics Research Project of PLA CLB20J033Military Medical Science and Technology Youth Cultivation Program Incubation Project 19QNP040PhD projects of Third Military Medical University JSKT201904the National Natural Science Foundation of China 81972080the Science and Technology Planning Project of Guangzhou City 201904010349
6 · The paper itself

Abstract

purposeTransoral approach can accomplish ventral decompression directly. However, surgical site infection (SSI) cannot be ignored. This paper aims to review the prevalence of infection and conduct advice for the treatment of SSI in the cervical spine following the transoral approach.

methodsA retrospective analysis of patients with SSI after transoral atlantoaxial reduction plate (TARP) surgery was performed. SSI was classified into three kinds according to the modified American CDC criteria.

results2.9% (17/581) patients who underwent TARP surgery, experienced SSI, of which five had superficial SSI (SI), eight had deep SSI (DI), and four had organ/space SSI (O/SI). The patients with SI underwent intravenous antibiotic treatment and were ultimately cured. Among the remaining 12 patients with DI and O/SI, 11 underwent reoperation for TARP system removal and subsequently one-stage posterior occipitocervical fixation, and one patient experienced infection two months post-operatively and died without receiving treatment. Among patients who underwent revision surgery, three experienced intracranial infection due to intra-operative dural tears, and continuous lumbar cerebrospinal fluid drainage and intrathecal injection of antibiotics were used as effective and appropriate treatments, with outcomes of one recovery and two deaths. All patients with SSI were begun on intravenous antibiotics with conversion to oral antibiotics.

conclusionsThe incidence of SSI was 2.9% (17/581). Adequate peri-operative preparation, early diagnosis, and appropriate treatment of SSI require further research.

Indexed as

Cervical VertebraeSurgical Wound InfectionAnti-Bacterial AgentsHumansIncidenceRetrospective StudiesAnti-Bacterial AgentsIncidenceSurgical site infectionTransoral approachTransoral atlantoaxial reduction plate

Identifiers

PMID35773531
OpenAlexW4283756049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.