ArticleNature cell biology2022
Dapl1 controls NFATc2 activation to regulate CD8
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In one paragraph
Article in Nature cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 42 citations in OpenAlex.
- POLE2 of tumor cells promotes OPN secretion based on PCLAF to drive M2 macrophage polarization in clear cell renal cell carcinoma.Cancer gene therapy · 2026Article
- An integrated machine learning and mendelian randomization approach identifies SERPING1 as a prognostic biomarker associated with CD8 + T-cell infiltration in DLBCL.Discover oncology · 2026Article
- DAPL1 is activated by Np63 and GRα and regulates lipid metabolism.Journal of molecular medicine (Berlin, Germany) · 2026Article
- Integrated clinicopathological, genomic, and immunophenotypic landscape of renal tubulocystic oncocytoma.Frontiers in immunology · 2026Article
- Non-redundant functions of NFATc1 in survival and NFATc2 in generation of exhausted CD8Frontiers in immunology · 2026Article
- Simultaneous generation of transplantable RGC-like and corneal progenitor cells from hiPSCs using a dual-lineage platform.Stem cell research & therapy · 2025Article
- Cisformer: a scalable cross-modality generation framework for decoding transcriptional regulation at single-cell resolution.Genome biology · 2025Article
- DAPL1 inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells by regulating the TGF-β/MITF pathway.Experimental eye research · 2025Article
- A Dapl1Science advances · 2025Article
- DAPL1 Identified as a Novel Prognostic Biomarker in Breast Cancer: Insights from Comprehensive in Silico Analysis.Iranian journal of biotechnology · 2025Article
- NFATC2/SERPINE1/JAK3/STAT3 signaling feedback loop in gastric cancer: immune evasion and anti-PD-1 resistance.Cell biology and toxicology · 2025Article
- The oral drug obeldesivir protects nonhuman primates against lethal Ebola virus infection.Science advances · 2025Article
- The NFATC2/Nrf2 cascade regulates spinal cord ischemia-reperfusion injury by controlling inflammation, apoptosis and oxidative stress.Regenerative therapy · 2025Article
- Death associated protein like 1 acts as a novel tumor suppressor in melanoma by increasing the stability of P21 protein.Molecular and cellular biochemistry · 2025Article
- Herpes stromal keratitis erodes the establishment of tissue-resident memory T cell pool in HSV-1 infected corneas.Mucosal immunology · 2025Article
- Combination adjuvant improves influenza virus immunity by downregulation of immune homeostasis genes in lymphocytes.ImmunoHorizons · 2025Article
- NFATC2 target gene signature correlates with immune checkpoint blockade resistance in melanoma.American journal of cancer research · 2025Article
- Multiomics profiles of genome-wide alterations in H3K27ac in different lung lobes after acute graft-Frontiers in immunology · 2025Article
- Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming.PLoS biology · 2024Article
- Characterization of the single cell landscape in normal and osteoarthritic equine joints.Annals of translational medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 3 countries.
Lele ZhuDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Lzhu6@hotmail.com.ORCID http://orcid.org/0000-0002-1732-8753
Xiaofei ZhouDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Meidi GuDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jiseong KimDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yanchuan LiDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Chun-Jung KoDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Xiaoping XieDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Tianxiao GaoDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Xuhong ChengDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Shao-Cong SunDepartment of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. ssun2018@outlook.com.ORCID http://orcid.org/0000-0001-7353-9400
The University of Texas MD Anderson Cancer Center · US
Funding
Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8MSignaling Functions of the Tumor Suppressor CYLDR01AI064639 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SUN, SHAO-CONG · 2006 to 2014
$3.6MRegulation of T-cell function and autoimmune inflammation by deubiquitinases.R37AI064639 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SUN, SHAO-CONG · 2015 to 2021
$2.8MNovaSeq6000S10OD024977 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUFF, VICKI · 2018 to 2018
$995kNCI NIH HHS P30 CA016672NIAID NIH HHS R01 AI064639NIAID NIH HHS R37 AI064639NIH HHS S10 OD024977
Abstract
CD8
Indexed as
CD8-Positive T-LymphocytesNeoplasmsHepatitis A Virus Cellular Receptor 2HumansMembrane ProteinsNFATC Transcription FactorsPersistent InfectionTranscription FactorsDAPL1 protein, humanHepatitis A Virus Cellular Receptor 2Membrane ProteinsNFATC2 protein, humanNFATC Transcription FactorsTranscription Factors
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.