Evidence map›Paper›PMID 35773360›Full record

ArticleScientific reports2022

Stressful life events and trajectories of depression symptoms in a U.S. military cohort.

Laura Sampson, Howard J Cabral, Anthony J Rosellini, Jaimie L Gradus, Gregory H Cohen, David S Fink, Anthony P King, Israel Liberzon, Sandro Galea

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Laura SampsonDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA. Lasampson@hsph.harvard.edu.
Howard J CabralDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Anthony J RoselliniCenter for Anxiety and Related Disorders, Department of Psychological and Brain Science, Boston University, Boston, MA, USA.
Jaimie L GradusDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Gregory H CohenDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
David S FinkNew York State Psychiatric Institute, New York, NY, USA.
Anthony P KingDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.
Israel LiberzonDepartment of Psychiatry, College of Medicine, Texas A&M University, College Station, TX, USA.
Sandro GaleaDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Boston University · USHarvard University · USNew York Psychoanalytic Society and Institute · USTexas A&M University · USUniversity of Michigan–Ann Arbor · US

Funding

CVD Epidemiology Training Program in Behavior, the Environment and Global HealthT32HL098048 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Goodarz Danaei, ERIC B RIMM · 2009 to 2026
$6.9M
NHLBI NIH HHS T32 HL098048NIH HHS T32 HL098048
6 · The paper itself

Abstract

Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse-including during childhood-and adult depression have been documented in many populations, but are less commonly assessed in military samples. We identified different trajectories of depression symptoms across four years in a military cohort using latent class growth analysis, and investigated the relationship between these trajectories and two domains of civilian life experiences: childhood adversity (e.g., being mistreated during childhood) and more proximal stressful experiences (e.g., divorce). A four-group depression model was identified, including a symptom-free group (62%), an increasing symptom group (13%), a decreasing symptom group (16%), and a "chronic" symptom group (9%). Compared to the symptom-free group, soldiers with childhood adversity were more likely to be in the chronic depression, decreasing, and increasing symptom groups. Time-varying adult stressors had the largest effect on depression symptoms for the increasing symptom group compared to other groups, particularly in the last two years of follow-up. This study indicates the importance of considering events from throughout the lifecourse-not only those from deployment-when studying the mental health of servicemembers.

Indexed as

Military PersonnelStress Disorders, Post-TraumaticAdultCohort StudiesDepressionHumansMental Health

Identifiers

PMID35773360
PMCPMC9246834
OpenAlexW4283725135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.