Evidence map›Paper›PMID 35773197›Full record

ArticleAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2022

Utility of Screening for Cognitive Impairment at Hospital Discharge in Adult Survivors of Critical Illness.

Gerardo Eman, Amber Marsh, Michelle Ng Gong, Aluko A Hope

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06677502 (The Usefulness of Cerebrolysin in Alleviating the Severity of Delirium in Critically Ill Patients), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06677502 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

The Usefulness of Cerebrolysin in Alleviating the Severity of Delirium in Critically Ill Patients

TypeinterventionalSponsorMedical University of LublinRan2024 to 2025Enrolled500ConditionsCognitive ImpairmentArmsCerebrolysin, Saline Solution - IV
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gerardo EmanGerardo Eman is an internal medicine resident, Albert Einstein College of Medicine, Bronx, New York.
Amber MarshAmber Marsh is a medical student, Albert Einstein College of Medicine, Bronx, New York.
Michelle Ng GongMichelle Ng Gong is division chief, Pulmonary and Critical Care Medicine, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Aluko A HopeAluko A. Hope is an associate professor of medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University, Portland, Oregon.
Albert Einstein College of Medicine · USOregon Health & Science University · US

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Duke University Molecular Imaging CenterR24CA092656 · NCI · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2001 to 2006
$3.7M
Prevention of Severe Acute Respiratory Failure in Patients with PROOFCheck - an EUH3HL125119 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI GAJIC, OGNJEN, GONG, MICHELLE NG · 2015 to 2018
$3.3M
Small Animal Imaging Resource ProgramU24CA092656 · NCI · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2007 to 2011
$2.2M
Einstein PETAL: Clinical Center for the PETAL NetworkU01HL122998 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI GONG, MICHELLE NG, RICHARDSON, LYNNE D. · 2014 to 2020
$1.9M
Cognitive Motor Interference Assessment for Improving Neurologic and Physical Disability Outcomes in Survivors of Severe Acute Respiratory Failure (CAMINANDO) Phase IIK01HL140279 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HOPE, ALUKO A. · 2018 to 2022
$885k
AHRQ HHS R18 HS026188NCATS NIH HHS UL1 TR001073NCI NIH HHS R24 CA092656NCI NIH HHS U24 CA092656NHLBI NIH HHS K01 HL140279NHLBI NIH HHS U01 HL122998NHLBI NIH HHS UH3 HL125119
6 · The paper itself

Abstract

backgroundFew studies have explored the utility of screening for cognitive impairment near hospital discharge in intensive care unit survivors.

objectivesTo explore baseline and hospitalization characteristics associated with cognitive impairment at hospital discharge and the relationship between cognitive impairment and 6-month disability and mortality outcomes.

methodsHospital disability status and treatment variables were collected from 2 observational cohort studies. Patients were screened for cognitive impairment at hospital discharge using the Montreal Cognitive Assessment (MoCA)-Blind, and telephone follow-up was conducted 6 months after discharge to assess vital and physical disability status.

resultsOf 423 patients enrolled, 320 were alive at hospital discharge. A total of 213 patients (66.6%) were able to complete the MoCA near discharge; 47 patients (14.7%) could not complete it owing to cognitive impairment. In MoCA completers, the median (IQR) score was 17 (14-19). Older age (β per year increase, -0.09 [95% CI, -0.13 to -0.05]) and blood transfusions during hospitalization (β, -1.20 [95% CI, -2.26 to -0.14]) were associated with lower MoCA scores. At 6-month follow-up, 176 of 213 patients (82.6%) were alive, of whom 41 (23.3%) had new severe physical disabilities. Discharge MoCA score was not significantly associated with 6-month mortality (adjusted odds ratio, 1.03 [95% CI, 0.93-1.14]) but was significantly associated with risk of new severe disability at 6 months (adjusted odds ratio, 0.85 [95% CI, 0.76-0.94]).

conclusionAssessing for cognitive impairment at hospital discharge may help identify intensive care unit survivors at higher risk of severe physical disabilities after critical illness.

Indexed as

Cognitive DysfunctionCritical IllnessAdultHospitalsHumansPatient DischargeSurvivors

Identifiers

PMID35773197
PMCPMC11756075
OpenAlexW4283750556

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.