Evidence map›Paper›PMID 35772943›Full record

ArticleInternational journal of STD & AIDS2022

Exploring drivers of pre-exposure prophylaxis uptake among gay, bisexual, and other men who have sex with men in Malaysia.

William H Eger, Adeleye Adaralegbe, Antoine Khati, Iskandar Azwa, Jeffrey A Wickersham, Sydney Osborne, Roman Shrestha

Open access · greenAbstract read
In one paragraph

Article in International journal of STD & AIDS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

William H EgerDepartment of Internal Medicine, Section of Infectious Diseases, 12228Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-4775-7313
Adeleye AdaralegbeDepartment of Allied Health Sciences, 7712University of Connecticut, Mansfield, CT, USA.
Antoine KhatiDepartment of Allied Health Sciences, 7712University of Connecticut, Mansfield, CT, USA.
Iskandar AzwaDepartment of Medicine, Faculty of Medicine, 37447University of Malaya, Kuala Lumpur, Malaysia.
Jeffrey A WickershamDepartment of Internal Medicine, Section of Infectious Diseases, 12228Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-7701-9162
Sydney OsborneDepartment of Allied Health Sciences, 7712University of Connecticut, Mansfield, CT, USA.
Roman ShresthaDepartment of Internal Medicine, Section of Infectious Diseases, 12228Yale School of Medicine, New Haven, CT, USA.
Mansfield University · USYale University · USUniversity of Malaya · MY

Funding

Development and Testing of a Mobile Application to Enhance HIV Prevention Cascade in Malaysian MSMR33TW011665 · FIC · UNIVERSITY OF CONNECTICUT STORRS · PI SHRESTHA, ROMAN · 2022 to 2024
$885k
Training in MHealth Prevention with MSMK01DA051346 · NIDA · YALE UNIVERSITY · PI SHRESTHA, ROMAN · 2020 to 2024
$862k
Integrated online-to-offline (O2O) model of care for HIV prevention and treatment among men who have sex with menR34MH130233 · NIMH · UNIVERSITY OF CONNECTICUT STORRS · PI SHRESTHA, ROMAN, WICKERSHAM, JEFFREY ALLEN · 2022 to 2024
$817k
Improving HIV testing and PrEP for transgender women through mHealthR21AI157857 · NIAID · YALE UNIVERSITY · PI SHRESTHA, ROMAN, WICKERSHAM, JEFFREY ALLEN · 2021 to 2022
$446k
Development and Testing of a Mobile Application to Enhance HIV Prevention Cascade in Malaysian MSMR21TW011665 · FIC · YALE UNIVERSITY · PI SHRESTHA, ROMAN · 2020 to 2021
$408k
FIC NIH HHS R21 TW011665FIC NIH HHS R33 TW011665NIAID NIH HHS R21 AI157857NIDA NIH HHS K01 DA051346NIMH NIH HHS R34 MH130233
6 · The paper itself

Abstract

backgroundPre-exposure prophylaxis (PrEP) is a valuable HIV prevention strategy, particularly among men who have sex with men (MSM); however, PrEP uptake is below the threshold needed to curb the HIV epidemic among this group, especially in settings like Malaysia, where same-sex sexual behavior is illegal.

methodsA sample of 355 participants completed an online survey between June and July 2020, recruited through geosocial networking apps for MSM and social networking websites (e.g. Facebook). We used descriptive and multivariable analyses to examine correlates of PrEP use within this population.

resultsThe sample was predominantly Malay (53.5%), had monthly incomes greater than RM 3000 (USD 730) (52.7%), and a tertiary level of education (84.5%). About 80% of participants heard of PrEP prior to the survey, with significantly less (18.3%) having ever taken PrEP. In the adjusted multivariable logistic model, using drugs before or during sexual intercourse ("chemsex") (AOR: 3.37; 95% CI: 1.44-7.89), being diagnosed with a sexually transmitted infection in the last 12 months (AOR: 2.08; 95% CI: 1.13-3.85), HIV testing in the previous 6 months (AOR: 3.23; 95% CI: 1.74-5.99), and disclosure of sexual orientation (AOR: 1.85; 95% CI: 1.02-3.34) were associated with having taken PrEP in the past.

conclusionsThis study revealed that PrEP use among Malaysian MSM is relatively low, despite high awareness, and is associated with healthcare engagement and high-risk behaviors. These results highlight the need to tailor outreach activities for individuals at increased risk for HIV and those disengaged with the health system.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesCoitusFemaleHomosexuality, MaleHumansMalaysiaMaleSexual Behaviorasiahigh-risk behaviorhomosexualhuman immunodeficiency virusprevention

Identifiers

PMID35772943
PMCPMC10069270
OpenAlexW4283737673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.