Evidence map›Paper›PMID 35772604›Full record

ReviewBrain research bulletin2022

Nervous system manifestations related to COVID-19 and their possible mechanisms.

Zhen Xie, Hao Hui, Zhihan Zhao, Wenjin Yu, Rui Wu, Yanzhao Zhu, Yuan Song, Bingqing Cao, Wenzhen Shi, Di Zhao and 10 more

Open access · hybridAbstract readReview
In one paragraph

Review in Brain research bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Editorial: Viral infection and brain diseases.Brain research bulletin · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 2 countries.

Zhen XieThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China; Medical Research Center; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No.3 Hospital, the Affiliated Hospital of Northwest University, No.10 Eastern section of the third FengCheng Rd., WeiYang District, Xi'an City, Shaanxi Province, P.R. China.
Hao HuiDepartment of Spine Surgery, Honghui Hospital, The Affiliated Hospital of Xi'an Jiaotong University, No. 555 Youyi East Road, Xi'an, Shaanxi 710054, PR China.
Zhihan ZhaoThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China.
Wenjin YuDepartment of Neurology, Yan'an University Medical College No. 3 Affiliated Hospital, Xianyang, China.
Rui WuDepartment of Neurology, Xijing Hospital, Air Force Medical University, No. 15 Changle West Road, Xi'an, Shaanxi 710032, PR China.
Yanzhao ZhuThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China.
Yuan SongThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China.
Bingqing CaoThe No.2 Department of Neurology, Shaanxi Provincial People's Hospital, No.256 Youyi West Road, Xi'an, Shaanxi 710068, PR China.
Wenzhen ShiMedical Research Center; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No.3 Hospital, the Affiliated Hospital of Northwest University, No.10 Eastern section of the third FengCheng Rd., WeiYang District, Xi'an City, Shaanxi Province, P.R. China.
Di ZhaoDepartment of Neurology, Xijing Hospital, Air Force Medical University, No. 15 Changle West Road, Xi'an, Shaanxi 710032, PR China.
Yunsong ZhaoDepartment of Neurology, Xijing Hospital, Air Force Medical University, No. 15 Changle West Road, Xi'an, Shaanxi 710032, PR China.
Junchao LvDepartment of Neurology, Xijing Hospital, Air Force Medical University, No. 15 Changle West Road, Xi'an, Shaanxi 710032, PR China.
Qian YaoThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China.
Yan DuanThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China.
Jingwen LiDepartment of Neurology, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, No. 2000 Xiang'an East Road, Xiamen, Fujian 361101, PR China.
Haijun ZhangDepartment of Neurology, Xijing Hospital, Air Force Medical University, No. 15 Changle West Road, Xi'an, Shaanxi 710032, PR China.
Linfu ZhouThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China.
Xiaotian WangSchool of Information and Communication Engineering, Xi'an Jiaotong University, No.28 Xianning West Road, Xi'an 710049, PR China.
Ye TianMedical Research Center; Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Xi'an No.3 Hospital, the Affiliated Hospital of Northwest University, No.10 Eastern section of the third FengCheng Rd., WeiYang District, Xi'an City, Shaanxi Province, P.R. China. Electronic address: chhty@sina.com.
Gang ZhaoThe College of Life Sciences and Medicine, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, PR China. Electronic address: 8683219@qq.com.
Northwest University · CNXijing Hospital · CNAir Force Medical University · CNResearch Medical Center · USShaanxi Provincial People's Hospital · CNXiamen University · CNXi'an Honghui Hospital · CNXi'an Jiaotong University · CNYan'an University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In December 2019, the novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection broke. With the gradual deepening understanding of SARS-CoV-2 and COVID-19, researchers and clinicians noticed that this disease is closely related to the nervous system and has complex effects on the central nervous system (CNS) and peripheral nervous system (PNS). In this review, we summarize the effects and mechanisms of SARS-CoV-2 on the nervous system, including the pathways of invasion, direct and indirect effects, and associated neuropsychiatric diseases, to deepen our knowledge and understanding of the relationship between COVID-19 and the nervous system.

Indexed as

COVID-19Nervous System DiseasesCentral Nervous SystemHumansPeripheral Nervous SystemSARS-CoV-2CNSCOVID-19NeuroinvasionNeurologyNeuropsychiatryPNSSARS-CoV-2

Identifiers

PMID35772604
PMCPMC9236920
OpenAlexW4283640395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.