Evidence map›Paper›PMID 35772067›Full record

ArticlePLoS pathogens2022

Key questions on the epigenetics of herpes simplex virus latency.

Abigail L Whitford, Anna R Cliffe

Abstract read
In one paragraph

Article in PLoS pathogens, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Co-option of mitochondrial nucleic acid-sensing pathways by HSV-1 UL12.5 for reactivation from latent infection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abigail L WhitfordDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America.
Anna R CliffeDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America.ORCID 0000-0003-1136-5171

Funding

INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3M
Cell stress-mediated changes in the Herpes simplex virus type 1 chromatin structure during reactivation from latent infectionR01NS105630 · NINDS · UNIVERSITY OF VIRGINIA · PI CLIFFE, ANNA RUTH · 2018 to 2022
$1.8M
IFN-dependent repression of HSV latency by PML-nuclear bodiesR21AI151340 · NIAID · UNIVERSITY OF VIRGINIA · PI CLIFFE, ANNA RUTH · 2020 to 2021
$444k
NIAID NIH HHS R21 AI151340NIAID NIH HHS T32 AI007046NINDS NIH HHS R01 NS105630
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Herpes SimplexEpigenesis, GeneticHumansSimplexvirusVirus ActivationVirus Latency

Identifiers

PMID35772067
PMCPMC9246395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.