ArticleACS chemical biology2022
Bringing Vibrational Imaging to Chemical Biology with Molecular Probes.
Article in ACS chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Illuminating aging with multimodal optical metabolic imaging.Science advances · 2026Review
- Diversification of the 10th core atom of 9-cyanopyronins expands the resonance Raman vibrational palette.Communications chemistry · 2026Article
- GFP-free live neuron quantitative imaging reveals compartmentalization and growth dynamics of polyQ aggregates.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Recent advances in Raman probes for multiplexed bioimaging.Inflammation and regeneration · 2025Review
- Feeling the vibes: Vibrational spectroscopic imaging of biomolecular assemblies in their natural environment.Applied physics reviews · 2025Article
- Electrostatic atlas of non-covalent interactions built into metal-organic frameworks.Nature chemistry · 2025Article
- Visualizing Thiol Stress Responses in Cells with a Water-Soluble Raman Sensor.Analytical chemistry · 2025Article
- Stimuli-responsive 'On-Off' SERS-darkfield bimodal plasmonic nanoprobes for selective cancer cell illumination.Biosensors & bioelectronics · 2025Article
- Illuminating life processes by vibrational probes.Nature methods · 2025Review
- DNA Origami-Engineered Plasmonic Nanoprobes for Targeted Cancer Imaging.Advanced functional materials · 2024Article
- Seeing is Believing: Developing Multimodal Metabolic Insights at the Molecular Level.ACS central science · 2024Review
- Critical Evaluation of Polarizable and Nonpolarizable Force Fields for Proteins Using Experimentally Derived Nitrile Electric Fields.Journal of the American Chemical Society · 2024Article
- Optical Photothermal Infrared - Fluorescence In Situ Hybridization (OPTIR-FISH).Journal of visualized experiments : JoVE · 2024Article
- Single-cell mapping of lipid metabolites using an infrared probe in human-derived model systems.Nature communications · 2024Article
- A Smart Intracellular Self-Assembling Bioorthogonal Raman Active Nanoprobe for Targeted Tumor Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Bond-selective fluorescence imaging with single-molecule sensitivity.Nature photonics · 2023Article
- Computational Design of Molecular Probes for Electronic Preresonance Raman Scattering Microscopy.The journal of physical chemistry. B · 2023Article
- Activatable Raman Probes Utilizing Enzyme-Induced Aggregate Formation for SelectiveJournal of the American Chemical Society · 2023Article
- Spatial sterol metabolism unveiled by stimulated Raman imaging.Frontiers in chemistry · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
As an emerging optical imaging modality, stimulated Raman scattering (SRS) microscopy provides invaluable opportunities for chemical biology studies using its rich chemical information. Through rapid progress over the past decade, the development of Raman probes harnessing the chemical biology toolbox has proven to play a key role in advancing SRS microscopy and expanding biological applications. In this perspective, we first discuss the development of biorthogonal SRS imaging using small tagging of triple bonds or isotopes and highlight their unique advantages for metabolic pathway analysis and microbiology investigations. Potential opportunities for chemical biology studies integrating small tagging with SRS imaging are also proposed. We next summarize the current designs of highly sensitive and super-multiplexed SRS probes, as well as provide future directions and considerations for next-generation functional probe design. These rationally designed SRS probes are envisioned to bridge the gap between SRS microscopy and chemical biology research and should benefit their mutual development.
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Registered trials
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