ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2022
Definition, diagnosis and clinical management of non-obstructive kidney dysplasia: a consensus statement by the ERKNet Working Group on Kidney Malformations.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The value of procalcitonin and urinary NGAL in the prediction of acute pyelonephritis and kidney scarring in pediatric patients with a history of febrile urinary tract infection: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- Prenatal body fluid analysis in the evaluation of CAKUT.Pediatric nephrology (Berlin, Germany) · 2026Review
- How we do it: functional magnetic resonance urography in congenital anomalies of the kidney and urinary tract.Pediatric radiology · 2026Review
- Renal dysplasia in horses: 25 cases (1991-2021).Journal of veterinary internal medicine · 2026Article
- Whole Exome Sequencing Reveals Promising Genes Associated with Congenital Renal Parenchymal Anomalies in Greek Children.Children (Basel, Switzerland) · 2026Article
- Biomarkers and Their Association with Kidney Scarring After the First Episode of Febrile Urinary Tract Infection or Vesicoureteral Reflux in Pediatric Patients.Medicina (Kaunas, Lithuania) · 2026Article
- European Reference Networks - a flagship activity of the EU in the field of rare and complex diseases: from 2017 to 2025.Orphanet journal of rare diseases · 2026Review
- Expression of ERK1/2, p38, and JNK in Normal Kidney Development and CAKUT.Medicina (Kaunas, Lithuania) · 2026Article
- Dissecting Normal and Abnormal Human Kidney Development Using Multiomics.Journal of the American Society of Nephrology : JASN · 2026Review
- Clinical and prognostic characteristics of renal hypodysplasia in children: insights from a 10-year single-center cohort.Pediatric nephrology (Berlin, Germany) · 2026Article
- Clinical exome sequencing efficacy and phenotypic expansions involving non-isolated congenital anomalies of kidney and urinary tract (CAKUT+).European journal of human genetics : EJHG · 2025Article
- Patterns of damage observed on dimercaptosuccinic acid kidney scans and future risk of urinary tract infections or reduced kidney function.Pediatric nephrology (Berlin, Germany) · 2025Article
- Kidney Function and Size in Children With Down Syndrome: A Cross-Sectional Study.Nephrology (Carlton, Vic.) · 2025Article
- From Intermittent Knee Pain to End-Stage Kidney Disease: An Atypical Presentation of Bilateral Kidney Dysplasia in an 11-Year-Old Girl.Case reports in pediatrics · 2025Article
- [The European Rare Kidney Disease Reference Network].Innere Medizin (Heidelberg, Germany) · 2024Review
- Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations.Stem cell reports · 2024Article
- Insights into Kidney Dysplasia in Duplex Kidneys: From Radiologic Diagnosis to Histopathologic Understanding.Biomedicines · 2024Article
- Congenital anomalies of the kidney and urinary tract: antenatal diagnosis, management and counselling of families.Pediatric nephrology (Berlin, Germany) · 2024Article
- Unilateral multicystic dysplastic kidney disease associated with ipsilateral ureteric bud remnant and contralateral duplex collecting system.Radiology case reports · 2023Article
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Authors and funding
23 authors at 19 institutions in 7 countries.
Funding
Abstract
Kidney dysplasia is one of the most frequent causes of chronic kidney failure in children. While dysplasia is a histological diagnosis, the term 'kidney dysplasia' is frequently used in daily clinical life without histopathological confirmation. Clinical parameters of kidney dysplasia have not been clearly defined, leading to imprecise communication amongst healthcare professionals and patients. This lack of consensus hampers precise disease understanding and the development of specific therapies. Based on a structured literature search, we here suggest a common basis for clinical, imaging, genetic, pathological and basic science aspects of non-obstructive kidney dysplasia associated with functional kidney impairment. We propose to accept hallmark sonographic findings as surrogate parameters defining a clinical diagnosis of dysplastic kidneys. We suggest differentiated clinical follow-up plans for children with kidney dysplasia and summarize established monogenic causes for non-obstructive kidney dysplasia. Finally, we point out and discuss research gaps in the field.
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