ArticleACS synthetic biology2022
Massively Parallel DNA Computing Based on Domino DNA Strand Displacement Logic Gates.
Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- DNA-Based Boolean Logic Gates for Molecular Computation and Biosensing: A Critical Review.Molecular biotechnology · 2026Review
- Enzyme-driven triplex structure-based DNA logic circuits.Journal of nanobiotechnology · 2025Article
- Integrating CRISPR-Cas12a with Aptamer as a Logic Gate Biosensing Platform for the Detection of CD33 and CD123.ACS omega · 2025Article
- Scalable DNA recognition circuits based on DNA strand displacement.Nanoscale advances · 2024Article
- Fluorescence-Based Multimodal DNA Logic Gates.Nanomaterials (Basel, Switzerland) · 2024Article
- Recent progress in stimuli-responsive DNA-based logic gates: Design, working principles and biological applications.Smart molecules : open access · 2024Review
- Programmable Biomolecule-Mediated Processors.Journal of the American Chemical Society · 2023Review
- A Tutorial Review on the Fluorescent Probes as a Molecular Logic Circuit-Digital Comparator.Molecules (Basel, Switzerland) · 2023Review
- Rapid microRNA detection method based on DNA strand displacement for ovarian cancer cells.Journal of Cancer · 2023Article
- DNA strand displacement based computational systems and their applications.Frontiers in genetics · 2023Review
- DNA computing for gastric cancer analysis and functional classification.Frontiers in genetics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA computing has gained considerable attention due to the characteristics of high-density information storage and high parallel computing for solving computational problems. Building addressable logic gates with biomolecules is the basis for establishing biological computers. In the current calculation model, the multiinput AND operation often needs to be realized through a multilevel cascade between logic gates. Through experiments, it was found that the multilevel cascade causes signal leakage and affects the stability of the system. Using DNA strand displacement technology, we constructed a domino-like multiinput AND gate computing system instead of a cascade of operations, realizing multiinput AND computing on one logic gate and abandoning the traditional multilevel cascade of operations. Fluorescence experiments demonstrated that our methods significantly reduce system construction costs and improve the stability and robustness of the system. Finally, we proved stability and robustness of the domino AND gate by simulating the tic-tac-toe process with a massively parallel computing strategy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.