ArticleProceedings of the National Academy of Sciences of the United States of America2022
A genetically linked pair of NLR immune receptors shows contrasting patterns of evolution.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 60 citations in OpenAlex.
- Contrasting evolutionary patterns of helper and sensor NRC NLRs in lettuce reflect functional divergence following subfunctionalization.PLoS genetics · 2026Article
- Subfamily-level comparative transcriptomics of key immune regulators in plants and suspension cells reveals novel rice blast resistance genes.Plant & cell physiology · 2026Article
- The wheat Yr6 locus, allelic to Pm5, harbors an NLR gene pair conferring stripe rust resistance.Plant communications · 2026Article
- The Landscape of Integrated Domains of Angiosperm NLR Genes Reveals Continuous Architecture Evolution of Plant Intracellular Immune Receptors.Plants (Basel, Switzerland) · 2025Article
- The pan-NLRome and diversity of Watkins wheat provide genetic resources for improving disease resistance and adaptation.Plant communications · 2025Article
- Research Progress on Rice-Blast-Resistance-Related Genes.Plants (Basel, Switzerland) · 2025Review
- Coordinated function of paired NLRs confers Yr84-mediated stripe rust resistance in wheat.Nature genetics · 2025Article
- Construction of the super pan-genome for the genusHorticulture research · 2025Article
- The resistance awakens: Diversity at the DNA, RNA, and protein levels informs engineering of plant immune receptors from Arabidopsis to crops.The Plant cell · 2025Review
- The Geographic Distribution and Natural Variation of the Rice Blast Fungus Avirulence GenePlants (Basel, Switzerland) · 2025Article
- Convergent reduction of immune receptor repertoires during plant adaptation to diverse special lifestyles and habitats.Nature plants · 2025Article
- Deciphering the landscape and evolutionary trajectory of NLR immune receptors in Dioscorea alata.Plant molecular biology · 2024Article
- A chromosome-scale genome assembly of Timorese crabgrass (Digitaria radicosa): a useful genomic resource for the Poaceae.G3 (Bethesda, Md.) · 2024Article
- Activation of an atypical plant NLR with an N-terminal deletion initiates cell death at the vacuole.EMBO reports · 2024Article
- NRC Immune receptor networks show diversified hierarchical genetic architecture across plant lineages.The Plant cell · 2024Article
- The NRC0 gene cluster of sensor and helper NLR immune receptors is functionally conserved across asterid plants.The Plant cell · 2024Article
- Subfunctionalization of NRC3 altered the genetic structure of the Nicotiana NRC network.PLoS genetics · 2024Article
- NLRC5 senses NADCell · 2024Article
- Evolution of wheat blast resistance gene Rmg8 accompanied by differentiation of variants recognizing the powdery mildew fungus.Nature plants · 2024Article
- An NLR paralog Pit2 generated from tandem duplication of Pit1 fine-tunes Pit1 localization and function.Nature communications · 2024Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 2 countries.
Funding
Abstract
Throughout their evolution, plant nucleotide-binding leucine-rich-repeat receptors (NLRs) have acquired widely divergent unconventional integrated domains that enhance their ability to detect pathogen effectors. However, the functional dynamics that drive the evolution of NLRs with integrated domains (NLR-IDs) remain poorly understood. Here, we reconstructed the evolutionary history of an NLR locus prone to unconventional domain integration and experimentally tested hypotheses about the evolution of NLR-IDs. We show that the rice (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.