Evidence map›Paper›PMID 35771857›Full record

ArticlePloS one2022

Psychiatric comorbidity and psychosocial stressors among people initiating HIV care in Cameroon.

Angela M Parcesepe, Lindsey M Filiatreau, Peter Vanes Ebasone, Anastase Dzudie, Brian W Pence, Milton Wainberg, Marcel Yotebieng, Kathryn Anastos, Eric Pefura-Yone, Denis Nsame and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Angela M ParcesepeDepartment of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.ORCID 0000-0002-4321-125X
Lindsey M FiliatreauDepartment of Psychiatry, School of Medicine, Washington University in St. Louis, St. Louis, MO, United States of America.ORCID 0000-0002-0355-4477
Peter Vanes EbasoneClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Anastase DzudieClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Brian W PenceDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Milton WainbergDepartment of Psychiatry and New York State Psychiatric Institute, Columbia University, New York, NY, United States of America.
Marcel YotebiengDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY, United States of America.
Kathryn AnastosDepartments of Medicine and Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, United States of America.
Eric Pefura-YoneJamot Hospital, Yaounde, Cameroon.
Denis NsameBamenda Regional Hospital, Bamenda, Cameroon.
Rogers AjehClinical Research Education Networking and Consultancy, Yaounde, Cameroon.
Denis NashInstitute for Implementation Science in Population Health, City University of New York, New York, NY, United States of America.
Albert Einstein College of Medicine · USUniversity of North Carolina at Chapel Hill · USBamenda University of Science and Technology · CMCity University of New York · USNew York Psychoanalytic Society and Institute · USWashington University in St. Louis · USYaoundé General Hospital · CM

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Understanding and addressing mental and substance use disorders among people living with HIV in low-resource settingsK01MH114721 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARCESEPE, ANGELA · 2018 to 2022
$766k
NIAID NIH HHS P30 AI050410NIAID NIH HHS U01 AI096299NICHD NIH HHS P2C HD050924NIMH NIH HHS K01 MH114721
6 · The paper itself

Abstract

backgroundPsychiatric comorbidity, the presence of two or more mental health disorders, has been associated with suboptimal HIV treatment outcomes. Little is known about the prevalence of psychiatric comorbidity among people with HIV (PWH) in sub-Saharan Africa.

methodsWe conducted interviews with PWH initiating HIV care in Cameroon between June 2019 and March 2020. Depression, anxiety, post-traumatic stress disorder (PTSD), and harmful drinking were dichotomized to represent those with and without symptoms of each. Psychiatric comorbidity was defined as having symptoms of two or more disorders assessed. Moderate or severe household hunger, high anticipatory HIV-related stigma, low social support, and high number of potentially traumatic events were hypothesized as correlates of psychiatric comorbidity. Bivariable log binomial regression models were used to estimate unadjusted associations between psychosocial stressors and psychiatric comorbidity.

resultsAmong 424 participants interviewed, the prevalence of psychiatric comorbidity was 16%. Among those with symptoms of at least one mental health or substance use disorder (n = 161), the prevalence of psychiatric comorbidity was 42%. The prevalence of psychiatric comorbidity was 33%, 67%, 76%, and 81% among those with symptoms of harmful drinking, depression, anxiety, and PTSD, respectively. Among individuals with symptoms of a mental health or substance use disorder, a high number of potentially traumatic events (prevalence ratio (PR) 1.71 [95% CI 1.21, 2.42]) and high anticipatory HIV-related stigma (PR 1.45 [95% CI 1.01, 2.09]) were associated with greater prevalence of psychiatric comorbidity.

conclusionPsychiatric comorbidity was common among this group of PWH in Cameroon. The effectiveness and implementation of transdiagnostic or multi-focus mental health treatment approaches in HIV care settings should be examined.

Indexed as

AlcoholismHIV InfectionsStress Disorders, Post-TraumaticSubstance-Related DisordersCameroonComorbidityHumansPrevalence

Identifiers

PMID35771857
PMCPMC9246197
OpenAlexW4283724856

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.