Evidence map›Paper›PMID 35771713›Full record

ReviewAndrology2023

Peyronie's disease development and management in diabetic men.

Simone Gianazza, Federico Belladelli, Riccardo Leni, Federica Masci, Piercarlo Rossi, Giuseppe Gianesini, Paolo Maggio, Emanuele Zaffuto, Andrea Salonia, Giulio Carcano and 2 more

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Andrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Simone GianazzaDepartment of Urology, University of Insubria, Varese, Italy.
Federico BelladelliDivision of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.
Riccardo LeniDivision of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.
Federica MasciDepartment of Urology, University of Insubria, Varese, Italy.
Piercarlo RossiDepartment of Urology, Circolo & Fondazione Macchi Hospital-ASST Sette Laghi, Varese, Italy.
Giuseppe GianesiniDepartment of Urology, Circolo & Fondazione Macchi Hospital-ASST Sette Laghi, Varese, Italy.
Paolo MaggioDepartment of Urology, Circolo & Fondazione Macchi Hospital-ASST Sette Laghi, Varese, Italy.
Emanuele ZaffutoDepartment of Urology, University of Insubria, Varese, Italy.
Andrea SaloniaDivision of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID 0000-0002-0595-7165
Giulio CarcanoDepartment of Urology, University of Insubria, Varese, Italy.
Federico DehòDepartment of Urology, University of Insubria, Varese, Italy.
Paolo CapogrossoDepartment of Urology, University of Insubria, Varese, Italy.ORCID 0000-0003-2347-9504
University of Insubria · ITOspedale di Circolo e Fondazione Macchi · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeyronie's disease (PD) is a fibrosing disorder of the penis resulting in plaque formation and penile deformity that negatively affect sexual and psychosocial function of patients. A multifactorial etiology of PD is assumed with diabetes mellitus (DM) being a potential risk factor.

objectivesThe aim of this narrative review was to investigate diabetes role in PD pathophysiology, diagnosis, and treatment. MATERIALS AND

methodsA non-systematic narrative review of original articles, meta-analyses, and randomized trials was conducted, including articles in the pre-clinical setting to support relevant findings.

resultsDiabetes is one of the most common comorbidity observed in PD patients, with a prevalence of about 11% and a strong association with erectile dysfunction (ED). DM is associated with both a higher risk of developing PD and has also an impact on the outcomes of PD's treatments. DISCUSSION: Evidence from literature underlines that metabolic alterations typical of DM are pivotal factors in the development of PD and resistance to its medical treatment.

conclusionThe role of DM in development of PD is still debated, while its role in PD development is not completely clear, there is a clear impact of DM on PD treatment outcomes.

Indexed as

Diabetes MellitusErectile DysfunctionPenile IndurationHumansMaleMeta-Analysis as TopicPenisRandomized Controlled Trials as TopicRisk Factorsdiabetes mellitusepidemiologyetiologypeyronie's disease

Identifiers

PMID35771713
OpenAlexW4283726286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.