Trial reportAmerican journal of respiratory and critical care medicine2022
Home High-Flow Nasal Cannula Oxygen Therapy for Stable Hypercapnic COPD: A Randomized Clinical Trial.
Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph
Trial report in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06204276 (The Physiologic Effects of Asymmetrical Versus Conventional High-flow Nasal Cannula in Acute Respiratory Failure. A Randomized Crossover Study.), which is not on this map. Cited by 64 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 4 pooled it
14.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Physiologic Effects of Asymmetrical Versus Conventional High-flow Nasal Cannula in Acute Respiratory Failure. A Randomized Crossover Study.
Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Impact of High-Flow Nasal Cannula for Chronic Obstructive Pulmonary Disease Exacerbation: A Systematic Review of Clinical and Physiological Outcomes.International journal of chronic obstructive pulmonary disease · 2026Pooled it
- Comparison of clinical outcomes between high-flow nasal cannula and non-invasive ventilation in acute exacerbation of COPD: a meta-analysis of randomized controlled trials.BMC pulmonary medicine · 2025Pooled it
- Home Respiratory Strategies in Patients With COPD With Chronic Hypercapnic Respiratory Failure.Respiratory care · 2024Pooled it
- Comparison of High-Flow Nasal Cannula with Conventional Oxygen Therapy in Patients with Hypercapnic Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.International journal of chronic obstructive pulmonary disease · 2023Pooled it
- Enhancing Respiratory Support in COPD Patients with Nasal High Flow Using an Asymmetrical Cannula Interface: A Randomized Cross-Over Study.International journal of chronic obstructive pulmonary disease · 2026Trial
- Home high-flow therapy during recovery from severe chronic obstructive pulmonary disease (COPD) exacerbation: a mixed-methods feasibility randomised control trial.BMJ open respiratory research · 2025Trial
- Automated Oxygen Delivery in Home Setting for Patients with COPD on Long-Term Oxygen Therapy - A Randomized Crossover Feasibility Trial.International journal of chronic obstructive pulmonary disease · 2025Trial
- The Effect of Heated, Humidified High-Flow Air in COPD Patients With Chronic Bronchitis.Pulmonary medicine · 2025Trial
- High flow nasal cannula oxygen therapy versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a randomized controlled non-inferiority trial.Critical care (London, England) · 2024Trial
- Bronchodilator Efficacy of High-Flow Nasal Cannula in COPD: Vibrating Mesh Nebulizer Versus Jet Nebulizer.Respiratory care · 2024Trial
- Home High-Flow Nasal Cannula Oxygen Therapy in a Chronic Obstructive Pulmonary Disease Patient with Chronic Stable Hypoxemic and Hypercapnic Respiratory Failure.Tuberculosis and respiratory diseases · 2026Article
- Diverging Trends in Home Respiratory Care in an Aging Society: National Data from Japan.JMA journal · 2026Article
- ERS Congress 2025: highlights from the Respiratory Intensive Care Assembly.ERJ open research · 2026Article
- The Efficacy of High-Flow Nasal Cannula (HFNC) Treatment in Patients with Chronic Type II Respiratory Failure Secondary to COPD.Journal of clinical medicine · 2026Article
- Article
- The long-term domiciliary oxygen therapy experience and needs in patients with chronic obstructive pulmonary disease: a qualitative meta-synthesis.Frontiers in rehabilitation sciences · 2026Review
- Research Hotspots and Future Trends of Oxygen Therapy for COPD: A Bibliometric and Visualization Analysis from 1973 to 2024.International journal of chronic obstructive pulmonary disease · 2026Article
- Narrative review: mucus plugging in chronic obstructive lung diseases and bronchiectasis.European clinical respiratory journal · 2026Review
- Management of hypercapnic acute respiratory failure with high-flow nasal cannula therapy: A narrative review.Annals of intensive care · 2026Review
- Practices of high-flow nasal therapy in acute and chronic respiratory failure: the Hi-Flow Survey.BMJ open respiratory research · 2025Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
40 authors at 20 institutions in 1 country.
Kazuma NagataDepartment of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
Takeo HorieDepartment of Respiratory Medicine, Japanese Red Cross Maebashi Hospital, Maebashi, Gunma, Japan.
Naohiko ChohnabayashiDivision of Pulmonary Medicine, Thoracic Center, St. Luke's International Hospital, Chuo-ku, Tokyo, Japan.
Torahiko JintaDivision of Pulmonary Medicine, Thoracic Center, St. Luke's International Hospital, Chuo-ku, Tokyo, Japan.
Ryosuke TsugitomiDivision of Pulmonary Medicine, Thoracic Center, St. Luke's International Hospital, Chuo-ku, Tokyo, Japan.
Akira ShirakiDepartment of Respiratory Medicine, Ogaki Municipal Hospital, Ogaki, Gifu, Japan.
Fumiaki TokiokaDepartment of Respiratory Medicine, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
Toru KadowakiDepartment of Pulmonary Medicine, National Hospital Organization Matsue Medical Center, Matsue, Shimane, Japan.ORCID 0000-0001-6064-4885
Akira WatanabeDepartment of Respiratory Medicine, National Hospital Organization Ehime Medical Center, Toon, Ehime, Japan.
Motonari FukuiRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Osaka, Japan.
Takamasa KitajimaRespiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Osaka, Japan.
Susumu SatoDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan.ORCID 0000-0002-9626-1090
Toru TsudaKirigaoka Tsuda Hospital, Kitakyushu, Fukuoka, Japan.
Nobuhito KishimotoDepartment of Respiratory Medicine, Takamastu Municipal Hospital, Takamatsu, Kagawa, Japan.
Hideo KitaDepartment of Respiratory Medicine, Takatsuki Red Cross Hospital, Takatsuki, Osaka, Japan.
Yoshihiro MoriDepartment of Respiratory Medicine, KKR Takamatsu Hospital, Takamatsu, Kagawa, Japan.
Masayuki NakayamaDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Kenichi TakahashiDepartment of Respiratory Medicine, Kishiwada City Hospital, Kishiwada, Osaka, Japan.
Tomomasa TsuboiDepartment of Respiratory Medicine, National Hospital Organization Minami Kyoto Hospital, Joyo, Kyoto, Japan.
Makoto YoshidaDepartment of Respiratory Medicine, National Hospital Organization Fukuoka National Hospital, Fukuoka, Fukuoka, Japan.
Osamu HatajiRespiratory Center, Matsusaka Municipal Hospital, Matsusaka, Mie, Japan.
Satoshi FukeDepartment of Respiratory Medicine, KKR Sapporo Medical Center, Sapporo, Hokkaido, Japan.
Michiko KagajoDepartment of Respiratory Medicine, Ogaki Municipal Hospital, Ogaki, Gifu, Japan.
Hiroki NishineDivision of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan.
Hiroyasu KobayashiRespiratory Center, Suzuka General Hospital, Suzuka, Mie, Japan.
Hiroyuki NakamuraDepartment of Respiratory Medicine, Sakaide City Hospital, Sakaide, Kagawa, Japan.
Miyuki OkudaOsaka Anti-Tuberculosis Association Osaka Hospital, Neyagawa, Osaka, Japan.ORCID 0000-0002-1954-1152
Sayaka TachibanaDepartment of Respiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan.
Shohei TakataDepartment of Respiratory Medicine, National Hospital Organization Fukuokahigashi Medical Center, Koga, Fukuoka, Japan.
Hisayuki OsoredaDepartment of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Yamaguchi, Japan.
Kenichi MinamiDepartment of Respiratory Medicine, Ishikiriseiki Hospital, Higashi-osaka, Osaka, Japan.
Takashi NishimuraDepartment of Respiratory Medicine, Kyoto Katsura Hospital, Kyoto, Kyoto, Japan.
Tadashi IshidaDepartment of Respiratory Medicine, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
Jiro TeradaDepartment of Respirology, Graduate School of Medicine, Chiba University, Chiba, Chiba, Japan.
Naoko TakeuchiDepartment of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, Osaka, Japan.
Yasuo KohashiDepartment of Respiratory Medicine, HARUHI Respiratory Medical Hospital, Kiyosu, Aichi, Japan.
Hiromasa InoueDepartment of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Kagoshima, Japan; and.
Yoko NakagawaDivision of Medical Statistics, Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Hyogo, Japan.
Takashi KikuchiDivision of Medical Statistics, Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Hyogo, Japan.
Keisuke TomiiDepartment of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
St. Luke's International Hospital · JPFoundation for Biomedical Research and Innovation · JPKitano Hospital · JPKobe City Medical Center General Hospital · JPKurashiki Central Hospital · JPNational Hospital Organization Takamatsu Medical Center · JPOgaki Municipal Hospital · JPAichi Medical University Hospital · JPChiba University · JPEhime Medical Center · JPEhime Prefectural Central Hospital · JPFukuoka Higashi Medical Center · JPFukuoka Hospital · JPIshikiriseiki Hospital · JPJichi Medical University · JPKagoshima University · JPKishiwada City Hospital · JPKyoto Katsura Hospital · JPKyoto Medical Center · JPKyoto University · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Noninvasive VentilationPulmonary Disease, Chronic ObstructiveRespiratory InsufficiencyAgedCannulaHumansHypercapniaOxygenOxygen Inhalation TherapyQuality of LifeOxygenchronic obstructive pulmonary diseasehypercapniaoxygen inhalation therapypulmonary diseaserespiratory insufficiency
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
NCT06204276ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.