Evidence map›Paper›PMID 35771496›Full record

SynthesisExperimental and clinical psychopharmacology2023

A systematic review and meta-analysis of interventions to induce attempts to quit tobacco among adults not ready to quit.

Elias M Klemperer, Joanna M Streck, Nicola Lindson, Julia C West, Alan Su, John R Hughes, Matthew J Carpenter

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Experimental and clinical psychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trends in Daily Cigarette Consumption Among Smokers: A Population Study in England, 2008-2023.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elias M KlempererVermont Center on Behavior & Health, Department of Psychiatry, University of Vermont.ORCID 0000-0002-7985-0870
Joanna M StreckTobacco Research & Treatment Center, Division of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School.
Nicola LindsonNuffield Department of Primary Care Health Sciences, University of Oxford.ORCID 0000-0003-2539-9268
Julia C WestVermont Center on Behavior & Health, Department of Psychiatry, University of Vermont.
Alan SuDepartment of Internal Medicine, University of Vermont Medical Center.
John R HughesVermont Center on Behavior & Health, Department of Psychiatry, University of Vermont.
Matthew J CarpenterDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina.ORCID 0000-0002-8909-1302

Funding

Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI KHADANGA, SHERRIE · 2013 to 2022
$21.3M
University of Vermont Tobacco Center of Regulatory ScienceU54DA036114 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HIGGINS, STEPHEN T · 2018 to 2022
$19.4M
Career Development Program in Substance Use and Addiction MedicineK12DA043490 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI A EDEN EVINS, NANCY A RIGOTTI · 2017 to 2026
$4.7M
FDA HHSNIDA NIH HHS K12 DA043490NIDA NIH HHS U54 DA036114NIGMS NIH HHS P20 GM103644
6 · The paper itself

Abstract

The prevalence of past-year smoking cessation remains below 10% in the U.S. Most who smoke are not ready to quit in the near future. Cessation requires both (a) initiating a quit attempt (QA) and (b) maintaining abstinence. Most research has focused on abstinence among people already motivated to quit. We systematically reviewed interventions to promote QAs among people not motivated to quit tobacco. We searched PubMed, CENTRAL, PsycINFO, Embase, and our personal libraries for randomized trials of tobacco interventions that reported QAs as an outcome among adults not ready to quit. We screened studies and extracted data in duplicate. We pooled findings of the 25 included studies using Mantel-Haenszel random effects meta-analyses when ≥ 2 studies tested the same intervention. Most (24) trials addressed cigarettes and one addressed smokeless tobacco. Substantial heterogeneity among trials resulted in a series of small meta-analyses. Findings indicate varenicline may increase QAs more than no varenicline,

Indexed as

Smoking CessationAdultBupropionHumansNicotianaNicotineNicotinic AgonistsTobacco Use Cessation DevicesBupropionNicotineNicotinic Agonists

Identifiers

PMID35771496
PMCPMC10106992

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.