Evidence map›Paper›PMID 35771469›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Human Bronchial Epithelial Cell Culture Models for Cigarette Smoke and Vaping Studies.

Niccolette Schaunaman, Kris Genelyn Dimasuay, Bruce Berg, Diana Cervantes, Hong Wei Chu

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Niccolette SchaunamanDepartment of Medicine, National Jewish Health, Denver, CO, USA.
Kris Genelyn DimasuayDepartment of Medicine, National Jewish Health, Denver, CO, USA.
Bruce BergDepartment of Medicine, National Jewish Health, Denver, CO, USA.
Diana CervantesDepartment of Medicine, National Jewish Health, Denver, CO, USA.
Hong Wei ChuDepartment of Medicine, National Jewish Health, Denver, CO, USA. chuhw@njhealth.org.
National Jewish Health · USUniversity of Colorado Denver · US

Funding

Tollip inhibits IL-33 signaling during airway influenza virus infectionU19AI125357 · NIAID · UNIVERSITY OF ARIZONA · PI KRAFT, MONICA · 2016 to 2025
$14.7M
Parkin in mitochondrial dysfunction and airway inflammation of obese asthmaR01AI152504 · NIAID · NATIONAL JEWISH HEALTH · PI CHU, HONG W, HOLGUIN, FERNANDO · 2020 to 2024
$3.7M
Novel Biased Beta2-AR Ligands as Asthma TherapeuticsR01AI161296 · NIAID · DUKE UNIVERSITY · PI CHU, HONG W, DICKEY, BURTON F · 2021 to 2025
$3.2M
Role of immunoproteasome in airway viral infectionR01AI150082 · NIAID · NATIONAL JEWISH HEALTH · PI CHU, HONG W · 2020 to 2024
$2.8M
Immunosuppressive injurious effects of e-cigarettes on human lung parenchymaR01HL144396 · NHLBI · NATIONAL JEWISH HEALTH · PI CHU, HONG W, PETRACHE, IRINA · 2018 to 2021
$1.9M
NHLBI NIH HHS R01 HL144396NIAID NIH HHS R01 AI150082NIAID NIH HHS R01 AI152504NIAID NIH HHS R01 AI161296NIAID NIH HHS U19 AI125357
6 · The paper itself

Abstract

Despite the continuing public health efforts to stop or reduce smoking, cigarette smoke use remains popular in the youth and adult population. A recent surge in the use of electronic cigarette and vaping products has created another major health challenge in public health. There is an urgent need to use physiologically relevant models to study the health effect of smoking or vaping in human subjects. Airway diseases such as bronchitis (Landman et al., CMAJ 191:E1321-E1331, 2019; Goniewicz, et al. Harm Reduct J 17:91, 2020; Xie et al., JAMA Netw Open 3:e2020816, 2020) have been described in people who smoke, vape, or both. Here, we will describe methods to collect, expand, and culture human airway epithelial cells from endobronchial brushings and expose these cells cultured at the air-liquid interface to cigarette smoke or electronic cigarette vapor.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsVapingAdolescentAdultEpithelial CellsHumansSmokingAir–liquid InterfaceAirway Epithelial CellsCigarette SmokeElectronic Cigarette

Identifiers

PMID35771469
PMCPMC9306142
OpenAlexW4285178749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.