Evidence map›Paper›PMID 35771460›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Modeling Asthma in Mice Using Common Aeroallergens.

Bidisha Paul Chowdhury, Magdalena M Gorska

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Bidisha Paul ChowdhuryDivision of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, Denver, CO, USA.
Magdalena M GorskaDivision of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, Denver, CO, USA. gorskam@njhealth.org.
National Jewish Health · USUniversity of Colorado Denver · US

Funding

Asthma susceptibility due to environmental programming of innate immunity in uteroR01HL122995 · NHLBI · NATIONAL JEWISH HEALTH · PI GORSKA, MAGDALENA MARIA · 2015 to 2024
$5.2M
Maternal programming of the stem cell-basophil axis for asthmaR01AI143837 · NIAID · NATIONAL JEWISH HEALTH · PI GORSKA, MAGDALENA MARIA · 2020 to 2024
$2.6M
NHLBI NIH HHS R01 HL122995NIAID NIH HHS R01 AI143837
6 · The paper itself

Abstract

Aeroallergens are common inducers of asthma in humans and are widely used in experimental research to generate animal models of this disease. In this chapter, we describe four mouse models of aeroallergen-induced asthma. These models differ in type and number of allergens used, route and duration of allergen exposure, and utilization of an adjuvant, representing different mechanistic variants of asthma. In addition, we describe several basic methods that are commonly used in mechanistic studies of asthma in mice. These methods include tracheotomy and bronchoalveolar lavage, cytospin and morphologic analysis of bronchoalveolar lavage cells, and lung harvest and digestion for generation of single-cell suspension.

Indexed as

AsthmaAllergensAnimalsBronchoalveolar Lavage FluidDisease Models, AnimalLungMiceMice, Inbred BALB COvalbuminAllergensOvalbuminAeroallergenAirway hyperresponsivenessAsthmaBronchoalveolar lavageInflammationMouse modelSensitization

Identifiers

PMID35771460
PMCPMC9721467
OpenAlexW4285203037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.