Evidence map›Paper›PMID 35771425›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Evaluation of Pharmaceutical Inhibition of Vasculogenic Mimicry In Vitro.

Joseph C Manarang, Alison McDermott

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joseph C ManarangCollege of Optometry, University of Houston, Houston, TX, USA. joseph_manarang@yahoo.com.
Alison McDermottCollege of Optometry, University of Houston, Houston, TX, USA.
University of Houston · US

Funding

Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI LAURA J. FRISHMAN · 1988 to 2026
$16.4M
Leukocyte Migration in Wounded CorneaR01EY017120 · NEI · UNIVERSITY OF HOUSTON · PI BURNS, ALAN R · 2007 to 2011
$1.8M
NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY017120
6 · The paper itself

Abstract

Vasculogenic mimicry formation is generally assessed using three-dimensional (3D) cultures of aggressive tumor cells grown over an extended incubation period. Test agents can be introduced during growth of the 3D cultures to determine their effect on vasculogenic mimicry formation. Here, we describe the protocol for evaluation of the inhibitory effect of drugs on vasculogenic mimicry in vitro using bright-field and fluorescence microscopy on 3D cultures of tumor cells grown in Matrigel.

Indexed as

Neovascularization, PathologicCell DifferentiationCell Line, TumorHumansPharmaceutical PreparationsPharmaceutical Preparations3D matrixChamber slidesFluorescence microscopyMatrigelTube formation assayVasculogenic mimicry

Identifiers

PMID35771425
OpenAlexW4285305492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.