ReviewExperimental physiology2022
Exertional heat stroke: an evidence based approach to clinical assessment and management.
Review in Experimental physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling.Molecular medicine reports · 2026Article
- Thermoregulatory and plasma neurobiomarker responses to heat tolerance assessment in exertional heat illness and matched controls.Experimental physiology · 2026Article
- The 2026 Men's FIFA Football World Cup: Evidence-Based Guidelines to Protect Player Health and Performance from Environmental Challenges.Sports medicine (Auckland, N.Z.) · 2026Review
- Prevalence and Risk Factors of Heat-Related Illness Among Pilgrims During the Hajj Season 2024: A Cross-Sectional Study.Journal of epidemiology and global health · 2026Article
- Heat intolerance: the challenge of returning to duty post-exertional heatstroke.Frontiers in sports and active living · 2026Review
- Article
- Mice develop obesity and lose myocardial metabolic flexibility months after exertional heat stroke.Communications biology · 2025Article
- Athlete's Hepatitis: A Case of a Young Healthy Male Developing Hypoxic Hepatitis After a Half-Marathon.Cureus · 2025Article
- Article
- Exertional Heatstroke Survivors' Knowledge and Beliefs About Exertional Heatstroke Diagnosis, Treatment, and Return to Play.Journal of athletic training · 2024Article
- Molecular Investigation and Preliminary Validation of Candidate Genes Associated with Neurological Damage in Heat Stroke.Molecular neurobiology · 2024Article
- Heat exhaustion and heat stroke among active component members of the U.S. Armed Forces, 2019-2023.MSMR · 2024Article
- Recommended water immersion duration for the field treatment of exertional heat stroke when rectal temperature is unavailable.European journal of applied physiology · 2024Article
- A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 3: Heat and cold tolerance during exercise.European journal of applied physiology · 2024Review
- Suspected exertional heat stroke: A case study of worker cooling in a hot and humid field environment.Work (Reading, Mass.) · 2024Article
- Exertional Heat Stroke and Rhabdomyolysis: A Medical Record Review and Patient Perspective on Management and Long-Term Symptoms.Sports medicine - open · 2023Article
- Neuromotor deficits and altered physiological responses to repeated exertional heat stroke exposures in mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Exertional heat stroke in sport and the military: epidemiology and mitigation.Experimental physiology · 2022Review
- Exertional heat stroke: pathophysiology and risk factors.BMJ medicine · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
NEW
findingsWhat is the topic of this review? The treatment of exertional heat stress, from initial field care through the return-to-activity decision. What advances does it highlight? Clinical assessment during field care using AVPU and vital signs to gauge recovery, approaches to field cooling and end of active cooling, and shared clinical decision making for return to activity recommendations. ABSTRACT: Exertional heat stroke (EHS) is a potentially fatal condition characterized by central nervous system (CNS) dysfunction and body temperature often but not always >40°C that occurs in the context of physical work in warm or hot environments. In this paper, we review the continuum of care, from initial recognition and field care to transport and hospital care, and finally return-to-duty considerations. Morbidity and mortality can be greatly reduced if not eliminated with prompt recognition and aggressive cooling. If medical personnel are not present at point of collapse during or immediately following exercise, EHS should be the presumptive diagnosis until a formal diagnosis can be determined by qualified medical staff. EHS is a rare medical situation where initial treatment (cooling) takes precedence over transport to a medical facility, where advanced medical care may be required for severe EHS casualties. Recovery from EHS and return to activity is usually straightforward and unremarkable provided the casualty is rapidly cooled at time of collapse and adequate time is allowed for body healing. However, evidence-based data to guide return to activity following EHS are limited. Current research suggests that most individuals recover completely within a few weeks though some individuals may suffer prolonged sequalae and additional evaluation may be warranted, including heat tolerance testing (HTT). Several aspects of the care of the EHS casualty are based on best practices derived from personal experience and continued research is necessary to optimize evaluation and management.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.