Evidence map›Paper›PMID 35771046›Full record

SynthesisJournal of dental research2022

Genome-wide Scan of Dental Fear and Anxiety Nominates Novel Genes.

Y Zhou, D W McNeil, S Haworth, T Dudding, J M Chernus, C Liu, D Liu, C D Wright, J Brumbaugh, C L Randall and 7 more

Open access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Etiology of Dental Anxiety and Dental Phobia: Review.European journal of dentistry · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Children's Dental Fear: Occurrence Mechanism and Prevention Guidance.Journal of multidisciplinary healthcare · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Y ZhouDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
D W McNeilDepartment of Psychology, West Virginia University, Morgantown, WV, USA.ORCID 0000-0002-0766-8455
S HaworthMedical Research Council Integrative Epidemiology Unit, Bristol Medical School, Bristol, UK.ORCID 0000-0001-7793-7326
T DuddingMedical Research Council Integrative Epidemiology Unit, Bristol Medical School, Bristol, UK.ORCID 0000-0003-3756-040X
J M ChernusDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
C LiuDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
D LiuDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
C D WrightDepartment of Psychology, West Virginia University, Morgantown, WV, USA.ORCID 0000-0003-1189-5877
J BrumbaughDepartment of Psychology, West Virginia University, Morgantown, WV, USA.
C L RandallDepartment of Oral Health Sciences, University of Washington School of Dentistry, Seattle, WA, USA.ORCID 0000-0002-5061-7450
R J WeyantDepartment of Dental Public Health, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
R J CroutDepartment of Periodontics, School of Dentistry, West Virginia University, Morgantown, WV, USA.
B FoxmanCenter for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.ORCID 0000-0001-6682-238X
S ReisThe Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA.
N J TimpsonMedical Research Council Integrative Epidemiology Unit, Bristol Medical School, Bristol, UK.
M L MarazitaDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
J R ShafferDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USWest Virginia University · USUniversity Of Bristol Dental Hospital · GBUniversity of Bristol · GBUniversity of Michigan · USUniversity of Washington · US

Funding

Psychosocial Influences on Rural Children's Oral HealthR01DE014899 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FOXMAN, BETSY, MARAZITA, MARY L. · 2002 to 2020
$39.9M
Racial Differences in Atherosclerosis, Plaque Vulnerability, and CVDR01HL089292 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2009 to 2010
$1.5M
Comparison of Diesel and Biodiesel Emissions and Health Effects in Underground MiR01OH009878 · OH · UNIVERSITY OF ARIZONA · PI BURGESS, JEFFEREY L. · 2012 to 2014
$1.4M
Dental Caries: Whole Genome Association and Gene x Environment StudiesU01DE018903 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARAZITA, MARY L. · 2007 to 2010
$1.2M
Medical Research CouncilNHLBI NIH HHS R01 HL089292NIDCR NIH HHS R01 DE014899NIDCR NIH HHS U01 DE018903NIOSH CDC HHS R01 OH009878Wellcome Trust 202802/Z/16/Z
6 · The paper itself

Abstract

Dental care-related fear and anxiety (DFA) is prevalent, affects oral health care utilization, and is related to poor oral health and decreased quality of life. In addition to learned and cultural factors, genetics is hypothesized to contribute to DFA. Therefore, we performed a genome-wide association study to identify genetic variants contributing to DFA. Adult and adolescent participants were from 4 cohorts (3 from the US-based Center for Oral Health Research in Appalachia,

Indexed as

Dental AnxietyQuality of LifeAdolescentAdultGenome-Wide Association StudyHumansLongitudinal StudiesNeurotensinNeurotensinbehavioral sciencegeneticsgenomicsGWAShereditymeta-analysis

Identifiers

PMID35771046
PMCPMC9608092
OpenAlexW4283717736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.