Evidence map›Paper›PMID 35770989›Full record

ArticleJournal of virology2022

Endocytosed HIV-1 Envelope Glycoprotein Traffics to Rab14

Huxley K Hoffman, Rebekah S Aguilar, Austin R Clark, Nicholas S Groves, Nairi Pezeshkian, Merissa M Bruns, Schuyler B van Engelenburg

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Virus infection and vesicle trafficking.Frontiers in immunology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huxley K HoffmanMolecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, Colorado, USA.
Rebekah S AguilarMolecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, Colorado, USA.
Austin R ClarkMolecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, Colorado, USA.
Nicholas S GrovesMolecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, Colorado, USA.
Nairi PezeshkianMolecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, Colorado, USA.
Merissa M BrunsMolecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, Colorado, USA.
Schuyler B van EngelenburgMolecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, Colorado, USA.ORCID 0000-0003-2100-3617
University of Denver · US

Funding

Identifying determinants of HIV-1 responsible for the nanoscale distribution and dynamics of virus assemblyR01AI138625 · NIAID · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI Schuyler van Engelenburg · 2018 to 2026
$3.3M
NIAID NIH HHS R01 AI138625
6 · The paper itself

Abstract

Production of infectious HIV-1 particles requires incorporation of the viral envelope glycoprotein (Env) at the plasma membrane (PM) of infected CD4

Indexed as

Endosomesenv Gene Products, Human Immunodeficiency VirusHIV-1HIV InfectionsLysosomesT-LymphocytesCell LineEndocytosisEpitopesHumansProtein Transportrab GTP-Binding Proteinsenv Gene Products, Human Immunodeficiency VirusEpitopesRab14 protein, humanrab GTP-Binding ProteinsendocytosisEnvenvelope glycoproteinHIV-1T celltrafficking

Identifiers

PMID35770989
PMCPMC9327703
OpenAlexW4283728976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.