Evidence map›Paper›PMID 35770660›Full record

ArticleGut and liver2023

Long-term Effects of the Eradication of

Jaehyung Park, Nayoung Kim, Won Seok Kim, Seon Hee Lim, Yonghoon Choi, Hyeong Ho Jo, Eunjeong Ji, Hyuk Yoon, Cheol Min Shin, Young Soo Park and 1 more

Abstract read
In one paragraph

Article in Gut and liver, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Outcomes ofGastroenterology and hepatology from bed to bench · 2026
    Review
  3. Article
  4. Effect ofGut and liver · 2025
    Article
  5. Article
  6. Observational
  7. The Role ofJournal of clinical medicine · 2024
    Review
  8. Effect ofPreventive medicine reports · 2024
    Article
  9. Impact ofFrontiers in gastroenterology (Lausanne, Switzerland) · 2024
    Review
  10. Effect ofJournal of neurogastroenterology and motility · 2023
    Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jaehyung ParkDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-1142-264X
Nayoung KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-9397-0406
Won Seok KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-1199-5707
Seon Hee LimDepartment of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.ORCID 0000-0001-6174-7165
Yonghoon ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-1331-969X
Hyeong Ho JoDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-4950-5435
Eunjeong JiMedical Research Collaborating Center, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-0483-606X
Hyuk YoonDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-2657-0349
Cheol Min ShinDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-2265-9845
Young Soo ParkDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0003-1893-7726
Dong Ho LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID 0000-0002-6376-410X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: Methods: This study included 2,267 subjects who visited a tertiary referral center between May 2003 and May 2019. HP was diagnosed by histology, a Results: Among 1,521 subjects, there was no difference in baseline metabolic parameters between the HP-uninfected (n=509) and HP-infected (n=1,012) groups, regardless of sex. Analysis of the metabolic parameters during follow-up among HP-uninfected (n=509), HP-non-eradicated (n=346), and HP-eradicated (n=666) groups showed that high-density lipoprotein (HDL) and the body mass index (BMI) increased after eradication, with a significant difference at 1-year of follow-up. In females, HDL increased after eradication (p=0.023), and the BMI increased after eradication in male subjects (p=0.010). After propensity score matching, the HDL change in female remained significant, but the statistical significance of the change in BMI in the male group became marginally significant (p=0.089). Conclusions: HP eradication affected metabolic parameters differently depending on sex. HDL significantly increased only in females over time, especially at 1-year of follow-up. In contrast, BMI showed an increasing tendency over time in males, especially at the 1-year follow-up.

Indexed as

Helicobacter InfectionsHelicobacter pyloriAnti-Bacterial AgentsBody Mass IndexFemaleFollow-Up StudiesHumansMaleRepublic of KoreaAnti-Bacterial AgentsEradicationMetabolic syndromeSex

Identifiers

PMID35770660
PMCPMC9840926

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.