Evidence map›Paper›PMID 35770254›Full record

ArticleEClinicalMedicine2022

Validation of the Decision model of the Burden of Hearing loss Across the Lifespan (DeciBHAL) in Chile, India, and Nigeria.

Ethan D Borre, Austin Ayer, Carolina Der, Titus Ibekwe, Susan D Emmett, Siddharth Dixit, Minahil Shahid, Bolajoko Olusanya, Suneela Garg, Mohini Johri and 5 more

Abstract read
In one paragraph

Article in EClinicalMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ethan D BorreDepartment of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.
Austin AyerDuke University School of Medicine, Durham, NC, USA.
Carolina DerFacultad de Medicina Universidad del Desarrollo, Clínica Alemana de Santiago, Santiago, Chile.
Titus IbekweDepartment of Ear, Nose and Throat, Head & Neck, University of Abuja Teaching Hospital, Gwagwalada Abuja, Nigeria.
Susan D EmmettDepartment of Head and Neck Surgery and Communication Sciences, Duke University School of Medicine, Durham, NC, USA.
Siddharth DixitDuke Global Health Institute, Duke University, Durham, NC, USA.
Minahil ShahidDuke Global Health Institute, Duke University, Durham, NC, USA.
Bolajoko OlusanyaCentre for Healthy Start Initiative, Lagos, Nigeria.
Suneela GargMaulana Azad Medical College and Associated Hospitals, New Delhi, India.
Mohini JohriDuke-Margolis Center for Health Policy, Duke University, Durham NC, USA.
James E SaundersDepartment of Surgery, Geisel School of Medicine, Dartmouth University, Lebanon, NH, USA.
Debara L TucciNational Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.
Blake S WilsonDepartment of Head and Neck Surgery and Communication Sciences, Duke University School of Medicine, Durham, NC, USA.
Osondu OgbuojiDepartment of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.
Gillian D Sanders SchmidlerDepartment of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
Economic Evaluation and Research Prioritization of Adult Hearing Screening in the USF30DC019846 · NIDCD · DUKE UNIVERSITY · PI BORRE, ETHAN D · 2021 to 2022
$88k
NCATS NIH HHS UL1 TR002553NIDCD NIH HHS F30 DC019846NIGMS NIH HHS T32 GM007171NIGMS NIH HHS T32 GM145449
6 · The paper itself

Abstract

Background: There is no published decision model for informing hearing health care resource allocation across the lifespan in low- and middle-income countries. We sought to validate the Decision model of the Burden of Hearing loss Across the Lifespan International (DeciBHAL-I) in Chile, India, and Nigeria. Methods: DeciBHAL-I simulates bilateral sensorineural hearing loss (SNHL) and conductive hearing loss (CHL) acquisition, SNHL progression, and hearing loss treatment. To inform model inputs, we identified setting-specific estimates including SNHL prevalence from the Global Burden of Disease (GBD) studies, acute otitis media (AOM) incidence and prevalence of otitis-media related CHL from a systematic review, and setting-specific pediatric and adult hearing aid use prevalence. We considered a coefficient of variance root mean square error (CV-RMSE) of ≤15% to indicate good model fit. Findings: The model-estimated prevalence of bilateral SNHL closely matched GBD estimates, (CV-RMSEs: 3.2-7.4%). Age-specific AOM incidences from DeciBHAL-I also achieved good fit (CV-RMSEs=5.0-7.5%). Model-projected chronic suppurative otitis media prevalence (1.5% in Chile, 4.9% in India, and 3.4% in Nigeria) was consistent with setting-specific estimates, and the incidence of otitis media-related CHL was calibrated to attain adequate model fit. DeciBHAL-projected adult hearing aid use in Chile (3.2-19.7% ages 65-85 years) was within the 95% confidence intervals of published estimates. Adult hearing aid prevalence from the model in India was 1.4-2.3%, and 1.1-1.3% in Nigeria, consistent with literature-based and expert estimates. Interpretation: DeciBHAL-I reasonably simulates hearing loss natural history, detection, and treatment in Chile, India, and Nigeria. Future cost-effectiveness analyses might use DeciBHAL-I to inform global hearing health policy. Funding: National Institutes of Health (3UL1-TR002553-03S3 and F30 DC019846).

Indexed as

Decision modelingGlobal health policyHearing loss

Identifiers

PMID35770254
PMCPMC9234074

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.