Evidence map›Paper›PMID 35769809›Full record

ArticleJAC-antimicrobial resistance2022

Implementation of an antimicrobial stewardship programme in three regional hospitals in the south-east of Liberia: lessons learned.

Abraham S Alabi, Stephen W Picka, Reubvera Sirleaf, Pacifique R Ntirenganya, Arnold Ayebare, Nidia Correa, Sarah Anyango, Gerald Ekwen, Emmanuel Agu, Rebecca Cook and 15 more

Open access · goldAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 6 institutions in 5 countries.

Abraham S AlabiHealth Focus GmbH, Friedrich-Ebert-Straße 33, 14469 Potsdam, Germany.
Stephen W PickaHealth Focus GmbH, Friedrich-Ebert-Straße 33, 14469 Potsdam, Germany.
Reubvera SirleafHealth Focus GmbH, Friedrich-Ebert-Straße 33, 14469 Potsdam, Germany.
Pacifique R NtirenganyaPartners In Health, Sophie Road Oldest, Congo Town, Monrovia, Liberia.
Arnold AyebarePartners In Health, Sophie Road Oldest, Congo Town, Monrovia, Liberia.
Nidia CorreaPartners In Health, Boston, MA, USA.
Sarah AnyangoPartners In Health, Sophie Road Oldest, Congo Town, Monrovia, Liberia.
Gerald EkwenPartners In Health, Sophie Road Oldest, Congo Town, Monrovia, Liberia.
Emmanuel AguMinistry of Health, Capitol Bye-Pass, Monrovia, Liberia.
Rebecca CookPartners In Health, Sophie Road Oldest, Congo Town, Monrovia, Liberia.
John YarngrorbleMinistry of Health, Capitol Bye-Pass, Monrovia, Liberia.
Ibrahim SanoeMinistry of Health, Capitol Bye-Pass, Monrovia, Liberia.
Henry DuguluMinistry of Health, Capitol Bye-Pass, Monrovia, Liberia.
Emmanuel WiefueMinistry of Health, Capitol Bye-Pass, Monrovia, Liberia.
Diana Gahn-SmithMinistry of Health, Capitol Bye-Pass, Monrovia, Liberia.
Francis N KatehMinistry of Health, Capitol Bye-Pass, Monrovia, Liberia.
Ezekiel F HallieSchool of Pharmacy, University of Liberia, Monrovia, Liberia.
Christiane G SidonieCentre de Recherches Medicales, CERMEL, Lambarene, Gabon.
Aaron O AboderinObafemi Awolowo University, Ile-Ife, Nigeria.
David VasselleeGerman Corporation for International Cooperation, GIZ, Tubman Boulevard, Congo Town, Monrovia, Liberia.
Damien BishopGerman Corporation for International Cooperation, GIZ, Tubman Boulevard, Congo Town, Monrovia, Liberia.
Daniel LohmannGerman Corporation for International Cooperation, GIZ, Tubman Boulevard, Congo Town, Monrovia, Liberia.
Manja Naumann-HustedtHealth Focus GmbH, Friedrich-Ebert-Straße 33, 14469 Potsdam, Germany.
Alois DörlemannHealth Focus GmbH, Friedrich-Ebert-Straße 33, 14469 Potsdam, Germany.
Frieder SchaumburgInstitute of Medical Microbiology, University of Münster, Münster, Germany.
University of Liberia · LRFocus (Germany) · DEPartners In Health · USCentre de Recherche Médicales de Lambaréné · GAObafemi Awolowo University · NGUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial stewardship (AMS) programmes can improve the use of antimicrobial agents. However, there is limited experience in the implementation of such programmes in low- and middle-income countries (LMICs). Objectives: To assess the effect of AMS measures in south-east Liberia on the quality of antimicrobial use in three regional hospitals. Methods: A bundle of three measures (local treatment guideline, training and regular AMS ward rounds) was implemented and quality indicators of antimicrobial use (i.e. correct compounds, dosage and duration) were assessed in a case series before and after AMS ward rounds. Primary endpoints were (i) adherence to the local treatment guideline; (ii) completeness of the microbiological diagnostics (according to the treatment guideline); and (iii) clinical outcome. The secondary endpoint was reduction in ceftriaxone use. Results: The majority of patients had skin and soft tissue infections ( Conclusions: AMS measures can improve the quality of antimicrobial use in LMICs. However, long-term engagement is necessary to make AMS programmes in LMICs sustainable.

Identifiers

PMID35769809
PMCPMC9226657
OpenAlexW4283465900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.