Review3 Biotech2022
Exosomal microRNAs (exoMIRs): micromolecules with macro impact in oral cancer.
Review in 3 Biotech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Integrative analysis of circulating tumor cells (CTCs) and exosomes from small-cell lung cancer (SCLC) patients: a comprehensive approach.Molecular oncology · 2025Article
- Innovative Applications of Nanopore Technology in Tumor Screening: An Exosome-Centric Approach.Biosensors · 2025Review
- Harnessing exosomes as cancer biomarkers in clinical oncology.Cancer cell international · 2024Review
- Review
- Role of Exosomes in Epithelial-Mesenchymal Transition.ACS applied bio materials · 2024Review
- Exosomal microRNA let-7c-5p enhances cell malignant characteristics by inhibiting TAGLN in oral cancer.Oncology research · 2024Article
- Exosomes in Bone Cancer: Unveiling their Vital Role in Diagnosis, Prognosis, and Therapeutic Advancements.Journal of Cancer · 2024Review
- Unlocking Exosome-Based Theragnostic Signatures: Deciphering Secrets of Ovarian Cancer Metastasis.ACS omega · 2023Review
- Clinical Theragnostic Signature of Extracellular Vesicles in Traumatic Brain Injury (TBI).ACS chemical neuroscience · 2023Review
- Connection between Radiation-Regulating Functions of Natural Products and miRNAs Targeting Radiomodulation and Exosome Biogenesis.International journal of molecular sciences · 2023Review
- Exosome and epithelial-mesenchymal transition: A complex secret of cancer progression.Journal of cellular and molecular medicine · 2023Article
- Review
- Exosome-Based Smart Drug Delivery Tool for Cancer Theranostics.ACS biomaterials science & engineering · 2023Review
- Modulating Effects of Cancer-Derived Exosomal miRNAs and Exosomal Processing by Natural Products.Cancers · 2023Review
- A comprehensive study based on exosome-related immunosuppression genes and tumor microenvironment in hepatocellular carcinoma.BMC cancer · 2022Article
- Regulation of Extracellular Vesicle-Mediated Immune Responses against Antigen-Specific Presentation.Vaccines · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exosomes are a sub-population of extracellular vesicles. It is released from all types of cells and are observed to be involved in cellular communications. It contains DNA, RNA, proteins and lipids. Tumor-derived exosomes can modify the tumor micro-environment and promote tumor development. Exosomal miRNAs are functionally linked with cancer progression, metastasis, and aggressive tumor phenotypes. In this review, we initially discuss on the fundamental biology of exosomes and then summarize the recent understanding of the exosomal miRNAs in oral cancer with various biological events. Moreover, the dynamic impact of exosomal miRNAs in the oral cancer micro-environment and their multiple parameter alterations can lead to (i) increased uncontrolled cell proliferation, (ii) oral cancer angiogenesis, (iii) oral cancer metastasis, (iv) drug resistance in oral cancer, (v) reprogramming of the immune system in oral cancer, and (vi) clinical significance of exosomal miRNA in oral cancer detection. Exosomes research can pave way to identify early detection tools in future and personalized medicine development for oral cancer. Thus, our review provides an informative biological insight into exosomal miRNAs in oral cancer, which can benefit the researchers working in the corresponding domain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.