ArticleFood chemistry. Molecular sciences2022
The effects of taurine supplementation on diabetes mellitus in humans: A systematic review and meta-analysis.
Article in Food chemistry. Molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Pooled it
- Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.Nutrition & diabetes · 2024Pooled it
- Zonisamide's Efficacy and Safety on Parkinson's Disease and Dementia with Lewy Bodies: A Meta-Analysis and Systematic Review.BioMed research international · 2022Pooled it
- Article
- Metabolic alterations in diabetic patients: aqueous humor profiling for biomarker discovery.Amino acids · 2025Article
- Do Sex and Gender Interact with the Biological Actions of Taurine? A Critical Rereading of the Literature.International journal of molecular sciences · 2025Review
- Molecular basis of human taurine transporter uptake and inhibition.Nature communications · 2025Article
- Article
- Exploring Salivary Metabolic Alterations in Type 2 Diabetes: Implications for Dental Caries and Potential Influences of HbA1c and Vitamin D Levels.Metabolites · 2024Article
- Article
- Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition.PloS one · 2024Article
- Emergence of taurine as a therapeutic agent for neurological disorders.Neural regeneration research · 2024Review
- Flattening the biological age curve by improving metabolic health: to taurine or not to taurine, that' s the question.Journal of geriatric cardiology : JGC · 2023Article
- Maternal and Child Health, Non-Communicable Diseases and Metabolites.Metabolites · 2023Review
- Impact of Diet Composition on Insulin Resistance.Nutrients · 2022Article
- Modification of Collagen Film via Surface Grafting of Taurine Molecular to Promote Corneal Nerve Repair and Epithelization Process.Journal of functional biomaterials · 2022Article
- Metabolism Meets Translation: Dietary and Metabolic Influences on tRNA Modifications and Codon Biased Translation.Wiley interdisciplinary reviews. RNAReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The ameliorative effect of taurine on diabetes has received extensive attention in recent years. Despite promising data from animal studies, the efficacy of taurine supplementation in human studies has been inconsistent. We thus did a meta-analysis of randomized controlled trials to assess the effect of taurine supplement on glycemic indices, serum lipids, blood pressure, body composition in patients with diabetes. Methods: We systematically searched PubMed, Embase, Cochrane, Web of Science, FDA.gov, and ClinicalTrials.gov for randomized controlled trials (published from inception to January 15, 2022; no language restrictions) about the effect of taurine supplement on diabetes. Values of Standardized Mean Differences (SMD) were determined for continuous outcomes. Results: Of 2206 identified studies, 5 randomized controlled trials were eligible and were included in our analysis (N = 209 participants). Compared with the control group, taurine could significantly reduce HbA1c (SMD -0.41[95% CI: -0.74, -0.09], p = 0.01), Fasting Blood Sugar (SMD - 1.28[95% CI: -2.42, -0.14], p = 0.03) and HOMA-IR (SMD - 0.64[95% CI: -1.22, -0.06], p = 0.03). In addition, taurine also reduced Insulin (SMD -0.48 [95% CI: -0.99, 0.03], p = 0.06) and TG (SMD -0.26 [95% CI: -0.55, 0.02], p = 0.07), but did not reach statistical significance. Conclusions: Taurine supplementation is beneficial in reducing glycemic indices, such as HbA1c, Fasting Blood Sugar, HOMA-IR in diabetic patients, but has no significant effect on serum lipids, blood pressure and body composition in diabetic patients. Taurine emerges as a new option for the management of patients with diabetes. Further studies are needed to understand the potential effect of taurine in diabetic patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.