Evidence map›Paper›PMID 35769335›Full record

ArticleFrontiers in molecular neuroscience2022

Frataxin Deficit Leads to Reduced Dynamics of Growth Cones in Dorsal Root Ganglia Neurons of Friedreich's Ataxia YG8sR Model: A Multilinear Algebra Approach.

Diana C Muñoz-Lasso, Belén Mollá, Jhon J Sáenz-Gamboa, Edwin Insuasty, Maria de la Iglesia-Vaya, Mark A Pook, Federico V Pallardó, Francesc Palau, Pilar Gonzalez-Cabo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Diana C Muñoz-LassoChemical Biology Group, Department of Biomedical Engineering, Eindhoven University of Technology (TU/e), Eindhoven, Netherlands.
Belén MolláDepartment of Genetics, Faculty of Biological Sciences, University of Valencia, Valencia, Spain.
Jhon J Sáenz-GamboaBrain Connectivity Laboratory, Joint Unit FISABIO & Prince Felipe Research Centre (CIPF), Valencia, Spain.
Edwin InsuastyThe Mathworks B.V., Eindhoven, Netherlands.
Maria de la Iglesia-VayaBrain Connectivity Laboratory, Joint Unit FISABIO & Prince Felipe Research Centre (CIPF), Valencia, Spain.
Mark A PookBiosciences, Brunel University London, Uxbridge, United Kingdom.
Federico V PallardóCIBER de Enfermedades Raras (CIBERER), Valencia, Spain.
Francesc PalauCIBER de Enfermedades Raras (CIBERER), Valencia, Spain.
Pilar Gonzalez-CaboCIBER de Enfermedades Raras (CIBERER), Valencia, Spain.
Instituto de Investigación de Enfermedades Raras · ESBrunel University of London · GBCentre for Biomedical Network Research on Rare Diseases · ESCentro de Investigacion Principe Felipe · ESEindhoven University of Technology · NLFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESHospital Sant Joan de Déu Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computational techniques for analyzing biological images offer a great potential to enhance our knowledge of the biological processes underlying disorders of the nervous system. Friedreich's Ataxia (FRDA) is a rare progressive neurodegenerative inherited disorder caused by the low expression of frataxin, which is a small mitochondrial protein. In FRDA cells, the lack of frataxin promotes primarily mitochondrial dysfunction, an alteration of calcium (Ca

Indexed as

DRG neuronsFriedreich’s ataxiagrowth conemultilinear algebraneurobiology of the diseasetensor decompositions

Identifiers

PMID35769335
PMCPMC9236133
OpenAlexW4282588699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.