Transcutaneous Cervical Vagus Nerve Stimulation Induces Changes in the Electroencephalogram and Heart Rate Variability of Healthy Dogs, a Pilot Study.

Gibrann Castillo, Luis Gaitero, Sonja Fonfara, Christopher J Czura, Gabrielle Monteith, Fiona James

Open access · goldAbstract read

In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 43% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Transcutaneous Auricular Vagus Nerve Stimulation Facilitates Cortical Arousal and Alertness.International journal of environmental research and public health · 2023
Trial

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gibrann CastilloDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Luis GaiteroDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Sonja FonfaraDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Christopher J CzuraConvergent Medical Technologies, Inc., Oyster Bay, NY, United States.

Gabrielle MonteithDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Fiona JamesDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcutaneous cervical vagus nerve stimulation (tcVNS) has been used to treat epilepsy in people and dogs. Objective electroencephalographic (EEG) and heart rate variability (HRV) data associated with tcVNS have been reported in people. The question remained whether EEG and electrocardiography (ECG) would detect changes in brain activity and HRV, respectively, after tcVNS in dogs. Simultaneous EEG and Holter recordings, from 6 client-owned healthy dogs were compared for differences pre- and post- tcVNS in frequency band power analysis (EEG) and HRV. The feasibility and tolerance of the patients to the tcVNS were also noted. In a general linear mixed model, the average power per channel per frequency band was found to be significantly different pre- and post-stimulation in the theta (

Indexed as

frequency band analysisheart rate variabilitypower spectral analysisSDNN indextranscutaneous cervical vagus nerve stimulationvagus nerve stimulation

Identifiers

PMID35769324

DOI10.3389/fvets.2022.878962

PMCPMC9234651

OpenAlexW4282551982

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.