Evidence map›Paper›PMID 35769183›Full record

ArticleOxford medical case reports2022

Successful weaning of a patient with severe COVID-19 pneumonia under prolonged midazolam sedation using morphine.

Kei Kunimasa, Yoshifumi Ohashi, Megumi Okawa, Hiroshi Iida, Shunji Sonoda, Yuki Hiuge, Masaaki Hachimine, Ai Yamamura, Takahisa Kawamura, Takako Inoue and 6 more

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kei KunimasaDepartment of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.ORCID https://orcid.org/0000-0002-5241-3486
Yoshifumi OhashiDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.
Megumi OkawaDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.
Hiroshi IidaDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.
Shunji SonodaDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.
Yuki HiugeDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.
Masaaki HachimineDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.
Ai YamamuraDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.
Takahisa KawamuraDepartment of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Takako InoueDepartment of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Motohiro TamiyaDepartment of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Hanako KuharaDepartment of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Kazumi NishinoDepartment of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Naoki NakamotoDepartment of Emergency and Critical Care, Osaka General Medical Center, Osaka, Japan.
Toru KumagaiDepartment of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan.
Hironobu TanigamiDepartment of Anesthesiology, Osaka International Cancer Institute, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic continues to spread around the world. In April 2021, Japan experienced a fourth wave of COVID-19 infections, which led to the breakdown of the medical system. Osaka, Japan, was particularly affected, with many severe cases and the highest number of COVID-19-associated deaths in Japan. Herein, we present a patient with severe COVID-19 infection who received prolonged midazolam (MDZ) treatment since propofol was not available due to shortage of medical resources. Moreover, the duration of mechanical ventilation was extended due to the development of a pneumothorax. When MDZ tapering was initiated, tachypnea was observed, which resulted failure in ventilator weaning. However, the use of continuous morphine infusion led a successful weaning off the ventilator. We suggest that the administration of morphine may allow for a smoother weaning process for some patients with severe COVID-19 infection.

Identifiers

PMID35769183
PMCPMC9235016

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.