Evidence map›Paper›PMID 35769175›Full record

ArticleThe Lancet regional health. Western Pacific2022

Genomic epidemiology of

Mark R Davies, Sebastian Duchene, Mary Valcanis, Aaron P Jenkins, Adam Jenney, Varanisese Rosa, Andrew J Hayes, Aneley Getahun Strobel, Liam McIntyre, Jake A Lacey and 14 more

Open access · goldAbstract read
In one paragraph

Article in The Lancet regional health. Western Pacific, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Laboratory epidemiology ofOne health (Amsterdam, Netherlands) · 2025
    Article
  4. Article
  5. Article
  6. Genetic heterogeneity in theMicrobial genomics · 2024
    Article
  7. Typhoid fever.Nature reviews. Disease primers · 2023
    Review
  8. Genomic Investigation ofMicroorganisms · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 10 institutions in 4 countries.

Mark R DaviesDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Sebastian DucheneDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Mary ValcanisMicrobiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
Aaron P JenkinsCentre for Ecosystem Management, Edith Cowan University, Western Australia.
Adam JenneyNew Vaccines Group, Murdoch Children's Research Institute, Victoria, Australia.
Varanisese RosaFiji Centre for Disease Control, Fiji Ministry of Health, Suva, Fiji.
Andrew J HayesDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Aneley Getahun StrobelDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Liam McIntyreDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Jake A LaceyDepartment of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute of Infection and Immunity, Victoria, Australia.
Elizabeth J KlemmWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
Vanessa K WongDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Aalisha SahukhanFiji Centre for Disease Control, Fiji Ministry of Health, Suva, Fiji.
Helen ThomsonNew Vaccines Group, Murdoch Children's Research Institute, Victoria, Australia.
Andrew PageWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
Dianna HockingDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Nancy WangDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Litia TudravuColonial War Memorial Hospital, Suva, Fiji.
Eric RafaiFiji Ministry of Health and Medical Services, Suva, Fiji.
Gordon DouganDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Benjamin P HowdenDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
John A CrumpCentre for International Health, Otago Medical School, University of Otago, Dunedin, New Zealand.
Kim MulhollandNew Vaccines Group, Murdoch Children's Research Institute, Victoria, Australia.
Richard A StrugnellDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
The University of Melbourne · AUMinistry Of Health · FJMurdoch Children's Research Institute · AUUniversity of Cambridge · GBColonial War Memorial Hospital · FJEdith Cowan University · AULondon School of Hygiene & Tropical Medicine · GBNorwich Research Park · GBUniversity of Otago · NZWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Typhoid fever is endemic in some Pacific Island Countries including Fiji and Samoa yet genomic surveillance is not routine in such settings. Previous studies suggested imports of the global H58 clade of Methods: Genomic sequencing approaches were implemented to study the distribution of 255 Findings: Genomic analyses showed Interpretation: Cyclones and flooding drove 'waves' of typhoid outbreaks in Fiji which, through population aggregation, poor sanitation and water safety, and then mobility of the population, spread clones more widely. Minimal international importations of new typhoid clones suggest that targeted local intervention strategies may be useful in controlling endemic typhoid infection. These findings add to our understanding of typhoid transmission networks in an endemic island country with broad implications, particularly across Pacific Island Countries. Funding: This work was supported by the Coalition Against Typhoid through the Bill and Melinda Gates Foundation [grant number OPP1017518], the Victorian Government, the National Health and Medical Research Council Australia, the Australian Research Council, and the Fiji Ministry of Health and Medical Services.

Indexed as

BayesianFijiOutbreakPhylodynamicsPhylogenyPopulation genomicsPublic healthSalmonella TyphiTyphoid fever

Identifiers

PMID35769175
PMCPMC9234096
OpenAlexW4283031021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.