Evidence map›Paper›PMID 35769084›Full record

ArticleFrontiers in endocrinology2022

GH Responsiveness Is not Correlated to

Anja Apel, Daniel I Iliev, Christina Urban, Karin Weber, Roland Schweizer, Gunnar Blumenstock, Sarah Pasche, Vanessa Nieratschker, Gerhard Binder

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anja ApelPediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Daniel I IlievPediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Christina UrbanPediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Karin WeberPediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Roland SchweizerPediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Gunnar BlumenstockDepartment of Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.
Sarah PascheDepartment of Psychiatry and Psychotherapy, Tübingen Center for Mental Health, University Hospital Tübingen, Tübingen, Germany.
Vanessa NieratschkerDepartment of Psychiatry and Psychotherapy, Tübingen Center for Mental Health, University Hospital Tübingen, Tübingen, Germany.
Gerhard BinderPediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
University Children's Hospital Tübingen · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The methylation of Objective: This study aimed to determine Design: This was a single tertiary center study analyzing clinical GH response and IGF-1 serum concentration changes in patients with GHD (n=40), SGA short stature (n=36), and Turner syndrome (n=16) treated with rhGH. Data were correlated to the methylation of two cytosine residues (-137, +97) of the P2 promoter of Results: Basal and stimulated IGF-1 concentrations, first year increment in height velocity and studentized residuals of a prediction model did not correlate to the methylation of -137 und +97 in Conclusions: This study did not confirm

Indexed as

DNA MethylationHuman Growth HormoneInsulin-Like Growth Factor ITurner SyndromeBody HeightChildHumansInfant, Small for Gestational AgePromoter Regions, GeneticHuman Growth HormoneIGF1 protein, humanInsulin-Like Growth Factor IGH responseGH treatmentIGF-1predictionpromotor methylationshort stature

Identifiers

PMID35769084
PMCPMC9235359
OpenAlexW4282568292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.