Evidence map›Paper›PMID 35769056›Full record

ArticleInternational journal of stem cells2022

Generation of Urothelial Cells from Mouse-Induced Pluripotent Stem Cells.

Dongxu Zhang, Fengze Sun, Huibao Yao, Di Wang, Xingjun Bao, Jipeng Wang, Jitao Wu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of stem cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dongxu ZhangDepartment of Urology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Fengze SunDepartment of Urology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Huibao YaoDepartment of Urology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Di WangDepartment of Urology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Xingjun BaoDepartment of Urology, The Second Clinical Medical College, Binzhou Medical University, Yantai, China.
Jipeng WangDepartment of Urology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Jitao WuDepartment of Urology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
Qingdao University · CNYuhuangding Hospital · CNBinzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: The search for a suitable alternative for urethral defect is a challenge in the field of urethral tissue engineering. Induced pluripotent stem cells (iPSCs) possess multipotential for differentiation. The Methods and Results: Our protocol made the visualization of differentiation processes of a 2-step approach possible. We firstly induced miPSCs into posterior definitive endoderm (DE) with glycogen synthase kinase-3 Conclusions: We built a model of directed differentiation of miPSCs into urothelial cells, which may provide the evidence for a regenerative potential of miPSCs in preclinical animal studies.

Indexed as

DifferentiationInduced pluripotent stem cellsTissue engineeringUrothelial cells

Identifiers

PMID35769056
PMCPMC9705153
OpenAlexW4283730753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.