Evidence map›Paper›PMID 35768999›Full record

ArticleCell proliferation2022

An optimized method for obtaining clinical-grade specific cell subpopulations from human umbilical cord-derived mesenchymal stem cells.

Yali Jia, Ailin Wang, Bichun Zhao, Chao Wang, Ruyu Su, Biao Zhang, Zeng Fan, Quan Zeng, Lijuan He, Xuetao Pei and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cell proliferation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  10. Improved therapeutic consistency and efficacy of CD317Stem cell research & therapy · 2024
    Article
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  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Yali JiaStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-2896-6021
Ailin WangStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.ORCID https://orcid.org/0000-0003-4657-4301
Bichun ZhaoStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.
Chao WangStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.
Ruyu SuSouth China Institute of Biomedicine, Guangzhou, China.
Biao ZhangStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.
Zeng FanSouth China Institute of Biomedicine, Guangzhou, China.
Quan ZengStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.
Lijuan HeSouth China Institute of Biomedicine, Guangzhou, China.
Xuetao PeiStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.
Wen YueStem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-3935-360X
Guangzhou Institutes of Biomedicine and Health · CNInstitute for Stem Cell Biology and Regenerative Medicine · IN

Funding

Guangzhou Health Care and Cooperative Innovation Major Project 201604020009Guangzhou Health Care and Cooperative Innovation Major Project 201803040005National Key Research and Development Program of ChinaThe National Key Research and Development Program of China 2017YFA0103100The National Key Research and Development Program of China 2017YFA0103103The National Nature Science Foundation of China 81671385
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are heterogeneous populations with broad application prospects in cell therapy, and using specific subpopulations of MSCs can enhance their particular capability under certain conditions and achieve better therapeutic effects. However, no studies have reported how to obtain high-quality specific MSC subpopulations in vitro culture. Here, for the first time, we established a general operation process for obtaining high-quality clinical-grade cell subpopulations from human umbilical cord MSCs (hUC-MSCs) based on particular markers. We used the MSC-CD106

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationCells, CulturedHumansReproducibility of ResultsUmbilical Cord

Identifiers

PMID35768999
PMCPMC9528761
OpenAlexW4283720099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.