Evidence map›Paper›PMID 35768951›Full record

ArticleToxicologic pathology2022

Inhalation of Silver Silicate Nanoparticles Leads to Transient and Differential Microglial Activation in the Rodent Olfactory Bulb.

Huong Huynh, Priya Upadhyay, Cora H Lopez, Malia K Miyashiro, Laura S Van Winkle, Sara M Thomasy, Kent E Pinkerton

Open access · greenAbstract read
In one paragraph

Article in Toxicologic pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Chemosensory tobacco product toxicology part 2: toxicological testing, assays, and state of the science.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Huong HuynhWilliam R Pritchard Veterinary Medical Teaching Hospital, University of California, Davis, Davis, California, USA.ORCID 0000-0002-2277-1821
Priya UpadhyayCenter for Health and the Environment, University of California, Davis, Davis, California, USA.
Cora H LopezCenter for Health and the Environment, University of California, Davis, Davis, California, USA.
Malia K MiyashiroCenter for Health and the Environment, University of California, Davis, Davis, California, USA.
Laura S Van WinkleCenter for Health and the Environment, University of California, Davis, Davis, California, USA.
Sara M ThomasyDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Kent E PinkertonCenter for Health and the Environment, University of California, Davis, Davis, California, USA.ORCID 0000-0001-6868-7572
University of California, Davis · USVeterinary Medical Teaching Hospital · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Targeted Research Training CoreT42OH008429 · OH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARRIS ADAMSON, CARISA · 2005 to 2024
$30.0M
UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ameer Taha · 2015 to 2026
$26.0M
Respiratory and Ocular Toxicity of Inhaled NanomaterialsU01ES027288 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PINKERTON, KENT ED, THOMASY, SARA MICHELLE · 2016 to 2020
$2.2M
NIEHS NIH HHS P30 ES023513NIEHS NIH HHS U01 ES027288NIH HHS P51 OD011107NIOSH CDC HHS T42 OH008429
6 · The paper itself

Abstract

Engineered silver nanoparticles (AgNPs), including silver silicate nanoparticles (Ag-SiO

Indexed as

Metal NanoparticlesSilverAerosolsAnimalsCalciumHeme Oxygenase-1MicrogliaOlfactory BulbRatsRats, Sprague-DawleyRodentiaSilicatesSilicon DioxideAerosolsCalciumHeme Oxygenase-1SilicatesSilicon DioxideSilverengineered nanomaterialsimmunohistochemistryinhalationmicroglianeurotoxicityolfactory bulbrodent study

Identifiers

PMID35768951
PMCPMC9529873
OpenAlexW4283727486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.