ArticleBMC geriatrics2022
Age-related differences of vastus lateralis muscle morphology, contractile properties, upper body grip strength and lower extremity functional capability in healthy adults aged 18 to 70 years.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Masseter muscle stiffness in bruxism and myofascial pain-related temporomandibular disorders: a systematic review and meta-analysis of quantitative ultrasound elastography studies.Oral radiology · 2026Pooled it
- The use of tensiomyography in older adults: a systematic review.Frontiers in physiology · 2023Pooled it
- Muscle point-of-care ultrasound as a predictor of mortality in older adults with hip fracture.European geriatric medicine · 2026Observational
- Intramuscular neural distribution of the vastus lateralis informs effective and safe botulinum neurotoxin injection.Scientific reports · 2026Article
- Analysis of muscle architecture variables and their relationship with functional capacity in patients with fibromyalgia: A cross-sectional study.Therapeutic advances in musculoskeletal disease · 2026Article
- What Is 'Muscle Health'? A Narrative Review and Conceptual Framework.Journal of functional morphology and kinesiology · 2025Review
- Reversing Decline in Aging Muscles: Expected Trends, Impacts and Remedies.Journal of functional morphology and kinesiology · 2025Review
- Comparative analysis of hand-held and stationary ultrasound for detection of sarcopenia in acutely hospitalised older adults-a validity and reliability study.European geriatric medicine · 2024Article
- Cross-sectional interactive associations of physical activity and sedentary behaviour with physical capacity across adulthood.Journal of cachexia, sarcopenia and muscle · 2024Article
- Ex-vivo validation of spatial gain sonography for the quantification of echo intensity in fascicle-aligned ultrasound images in ten anatomical muscles in Bos taurus.Scientific reports · 2024Article
- Correlation between Physical Performance and Tensiomyographic and Myotonometric Parameters in Older Adults.Healthcare (Basel, Switzerland) · 2023Article
- Effectiveness of a Multicomponent Training Program on Physical Performance and Muscle Quality in Older Adults: A Quasi-Experimental Study.International journal of environmental research and public health · 2022Article
- Time spent in moderate‑ to vigorous‑intensity physical activity is associated with lower limb muscle thickness in collegiate healthy young women without regular exercise habits.Medicine internationalArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a lack of of cross-sectional research that has investigated muscle morphology, function, and functional capability in all age-bands of healthy adults. The primary aim of this study was to evaluate age-related differences in indices of vastus lateralis (VL) muscle morphology, function and functional capability in a sample of healthy males and females aged 18-70yrs. Secondary aims were to evaluate relationships between age and VL muscle morphology and function and functional capability.
methodsB mode Ultrasonography and Tensiomyography were used to measure VL muscle thickness, pennation angle, fascicle length, and contractile properties in 274 healthy adults aged 18-70yrs. Measurements of grip strength and functional capability (1-min chair rise test) were also taken. Data analysis included descriptive statistics, correlations, one-way ANOVAs, and multiple regressions.
resultsNegative correlations were found between age and muscle thickness (r
conclusionAge-related differences in muscle health are noticeable at 50 years of age, and age-related differences are larger in females compared to males. It was suggested that the thickness of the VL changed the most with age across the adult lifespan and that physical activity likely acts to abate detrimental change.
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Registered trials
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