ArticleBMC pregnancy and childbirth2022
Prepregnancy body mass index, gestational weight gain, and maternal prepartum inflammation in normal pregnancies: findings from a Chinese cohort.
Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 citing papers in PubMed, 13 citations in OpenAlex.
- Article
- The potential effect modifying role of nutrition, physical activity, and body mass index on the association between air pollution and adverse birth and early-life health outcomes: a scoping review.Environmental research communications · 2025Article
- Excessive Pregestational Weight and Maternal Obstetric Complications: The Role of Adipokines.International journal of molecular sciences · 2023Review
- Ethnic Disparities and Obesity Risk Factors in Pregnant Women: A Retrospective Observational Cohort Study.Nutrients · 2023Observational
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundObesity has been linked to systemic inflammation in population studies.
objectiveTo examine the associations of prepregnancy body mass index (pBMI) and total gestational weight gain (tGWG) with maternal prepartum low-grade inflammation (LGI) and clinically significant inflammation (CSI) defined by serum C-reactive protein (CRP) concentration.
methodsFive thousand four hundred seventy-six Chinese women with uncomplicated pregnancies and recorded data on pBMI and prepartum body weight were included in this study. Blood samples were drawn before delivery for high-sensitivity CRP assay. Inadequate, optimal, and excessive tGWG were defined using the Institute of Medicine's recommendation. Multivariable Poisson regressions were used to estimate relative risks (RRs) for having prepartum LGI and CSI (defined as CRP concentration 3-10 and > 10 mg/L, respectively) across pBMI and tGWG categories.
resultsThe mean pBMI, mean tGWG, and median maternal prepartum CRP concentration were 20.4 kg/m
conclusionsPrepregnancy overweight/obesity and excessive tGWG increase the risk of maternal prepartum systemic inflammation, which further highlights the importance of weight management before and during pregnancy.
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