ArticleScientific reports2022
Analysis of the physiological load on lumbar vertebrae in patients with osteoporosis: a finite-element study.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Biomechanical comparison of lumbar rotational manipulations in two different positions using force measurement and finite element analysis.Chiropractic & manual therapies · 2026Trial
- Hounsfield unit threshold to predict lumbar fusion failure: a finite element study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Evaluation of a Novel Flexible Cage System for C5-C6 Fixation: A Finite Element Study Against Conventional ACDF Implants.Bioengineering (Basel, Switzerland) · 2026Article
- SDC4 drives fibrotic remodeling of the intervertebral disc under altered spinal loading.Cell death & disease · 2025Article
- Co-morbid mechanisms of intervertebral disc degeneration and osteoporosis: biomechanical coupling and molecular pathways synergistically driving degenerative lesions.Journal of orthopaedic surgery and research · 2025Review
- Finite Element Analysis of Biomechanical Assessment: Traditional Bilateral Pedicle Screw System vs. Novel Reverse Transdiscal Screw System for Lumbar Degenerative Disc Disease.Bioengineering (Basel, Switzerland) · 2025Article
- Correlation analysis of lumbar disc degeneration characteristics and bone mineral density in patients with osteoporosis based on the Roussouly classification.Quantitative imaging in medicine and surgery · 2025Article
- A Finite Element Study of Simulated Fusion in an L4-L5 Model: Influence of the Combination of Materials in the Screw-and-Rod Fixation System on Reproducing Natural Bone Behavior.Biomimetics (Basel, Switzerland) · 2025Article
- Impact of BMI, osteoporosis, and disc degeneration on post-UBE lumbar stability: a finite element analysis of nonlinear synergistic effects.Frontiers in bioengineering and biotechnology · 2025Article
- Genetic Insights Into the Relationship Between Menstrual Factors and Site-/Age-Specific Bone Mineral Density.International journal of genomics · 2025Article
- Biomechanical changes in lumbar intervertebral discs after percutaneous endoscopic transforaminal discectomy surgery at different Body Mass Index (BMI) categories.Journal of orthopaedic surgery and research · 2024Article
- Risk Factors for Bone Cement Displacement After Percutaneous Kyphoplasty in Osteoporotic Vertebral Fractures: A Retrospective Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Article
- Disc degeneration influences the strain magnitude and stress distribution within the adjacent trabecular bone.Frontiers in bioengineering and biotechnology · 2024Article
- Comparing zero-profile and conventional cage and plate in anterior cervical discectomy and fusion using finite-element modeling.Scientific reports · 2023Article
- Biomechanical Effects of Different Sitting Postures and Physiologic Movements on the Lumbar Spine: A Finite Element Study.Bioengineering (Basel, Switzerland) · 2023Article
- Effect of Interbody Implants on the Biomechanical Behavior of Lateral Lumbar Interbody Fusion: A Finite Element Study.Journal of functional biomaterials · 2023Article
- Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis.Frontiers in endocrinology · 2023Article
- Biomechanical evaluation of different posterior fixation techniques for treating thoracolumbar burst fractures of osteoporosis old patients: a finite element analysis.Frontiers in bioengineering and biotechnology · 2023Article
- A comparative analysis of using cage acrossing the vertebral ring apophysis in normal and osteoporotic models under endplate injury: a finite element analysis.Frontiers in bioengineering and biotechnology · 2023Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to investigate the difference in physiological loading on the spine in three different motions (flexion-extension, lateral bending, and axial rotation) between osteoporotic and normal spines, using finite element modelling. A three-dimensional finite element (FE) model centered on the lumbar spine was constructed. We applied two different material properties of osteoporotic and normal spines. For the FE analysis, three loading conditions (flexion-extension, lateral bending, and axial rotation) were applied. The von Mises stress was higher on the nucleus pulposus at all vertebral levels in all movements, in the osteoporosis group than in the normal group. On the annulus fibrosus, the von Mises stress increased at the level of L3-L4, L4-L5, and L5-S in the flexion-extension group and at L4-L5 and L5-S levels in the lateral bending group. The values of two motions, flexion-extension and lateral bending, increased in the L4 and L5 cortical bones. In axial rotation, the von Mises stress increased at the level of L5 of cortical bone. Additionally, the von Mises stress increased in the lower endplate of L5-S and L4-L5 in all movements, especially lateral bending. Even in the group with no increase, there was a part that received increased von Mises stress locally for each element in the three-dimensional reconstructed view of the pressure distribution in color. The von Mises stress on the lumbar region in the three loading conditions, was greater in most components of osteoporotic vertebrae than in normal vertebrae and the value was highest in the nucleus pulposus. Considering the increase in the measured von Mises stress and the local increase in the pressure distribution, we believe that these results can contribute to explaining discogenic pain and degeneration.
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