ArticleNature communications2022
Rhythmic interactions between the mediodorsal thalamus and prefrontal cortex precede human visual perception.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Hands off, brain off? A meta-analysis of neuroimaging data during active and passive driving.Brain and behavior · 2023Pooled it
- Rhythmic stimulation elicits multiple, concurrent neural responses.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Alpha Oscillations Track the Projection of Reactivated Memories into Conscious Awareness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Network-nodal tACS induces right-lateralization of thalamocortical connectivity.Scientific reports · 2026Article
- Rhythmic sampling of multiple decision alternatives in the human brain.Nature communications · 2026Article
- Through Massage to the Brain-Neuronal and Neuroplastic Mechanisms of Massage Based on Various Neuroimaging Techniques (EEG, fMRI, and fNIRS).Journal of clinical medicine · 2026Review
- From network hub to therapeutic target: the role of mediodorsal thalamic nucleus in epilepsy.Frontiers in neuroscience · 2026Review
- A biophysical framework for conscious state transitions based on intrinsic neuronal properties: the dynamic contextual element memory (DCEM) model.Frontiers in systems neuroscience · 2026Article
- EphB1-NR2B receptor signaling in glutamatergic neurons of the ventroposteromedial thalamic nucleus regulates emergence from anesthesia.Science advances · 2025Article
- Neural Representation of Associative Threat Learning in Pulvinar Divisions, Lateral Geniculate Nucleus, and Mediodorsal Thalamus in Humans.bioRxiv : the preprint server for biology · 2025Article
- Visual hallucinations in Parkinson's disease: spotlight on central cholinergic dysfunction.Brain : a journal of neurology · 2025Review
- Oscillations in an artificial neural network convert competing inputs into a temporal code.PLoS computational biology · 2024Article
- Thalamocortical architectures for flexible cognition and efficient learning.Trends in cognitive sciences · 2024Review
- Original speech and its echo are segregated and separately processed in the human brain.PLoS biology · 2024Article
- Neural mechanisms of domain-general inhibitory control.Trends in cognitive sciences · 2023Review
- Fronto-parietal networks shape human conscious report through attention gain and reorienting.Communications biology · 2023Article
- The effect of familiarity on behavioral oscillations in face perception.Scientific reports · 2023Article
- Altered structural covariance of locus coeruleus in individuals with significant memory concern and patients with mild cognitive impairment.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- A quantitative model reveals a frequency ordering of prediction and prediction-error signals in the human brain.Communications biology · 2022Article
- Rhythmic interactions between the mediodorsal thalamus and prefrontal cortex precede human visual perception.Nature communications · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The thalamus is much more than a simple sensory relay. High-order thalamic nuclei, such as the mediodorsal thalamus, exert a profound influence over animal cognition. However, given the difficulty of directly recording from the thalamus in humans, next-to-nothing is known about thalamic and thalamocortical contributions to human cognition. To address this, we analysed simultaneously-recorded thalamic iEEG and whole-head MEG in six patients (plus MEG recordings from twelve healthy controls) as they completed a visual detection task. We observed that the phase of both ongoing mediodorsal thalamic and prefrontal low-frequency activity was predictive of perceptual performance. Critically however, mediodorsal thalamic activity mediated prefrontal contributions to perceptual performance. These results suggest that it is thalamocortical interactions, rather than cortical activity alone, that is predictive of upcoming perceptual performance and, more generally, highlights the importance of accounting for the thalamus when theorising about cortical contributions to human cognition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.