Evidence map›Paper›PMID 35768218›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Autoimmune Encephalitis Associated with Anti-N-methyl-D-aspartate Receptor and Anti-Hu Antibodies Successfully Treated with Carboplatin and Etoposide for Small-cell Lung Cancer.

Ryogo Shobatake, Aya Kumazawa, Noriko Koyama, Nobuyuki Takahashi

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ryogo ShobatakeDepartment of Neurology, Nara City Hospital, Japan.
Aya KumazawaDepartment of Neurology, Nara City Hospital, Japan.
Noriko KoyamaDepartment of Respiratory Medicine, Nara City Hospital, Japan.
Nobuyuki TakahashiDepartment of Neurology, Nara City Hospital, Japan.
Nara City Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coexistence of multiple autoantibodies associated with autoimmune encephalitis (AE) is rare. A 63-year-old woman developed psychosis and consciousness disorder. Her cerebrospinal fluid was positive for anti-N-methyl-D-aspartate receptor antibodies, and her serum was positive for anti-Hu antibodies. Enhanced computed tomography revealed a mass in the right pulmonary hilum. AE complicated with small-cell lung cancer was diagnosed. Immunotherapy (steroid therapy and intravenous immunoglobulin) and four courses of carboplatin-etoposide chemotherapy were required to improve her neurological symptoms. When the coexistence of multiple antibodies is detected, despite its rarity, aggressive detection and treatment of any underlying malignancy may be recommended.

Indexed as

Anti-N-Methyl-D-Aspartate Receptor EncephalitisLung NeoplasmsAutoantibodiesCarboplatinEncephalitisEtoposideFemaleHashimoto DiseaseHumansMiddle AgedReceptors, Amino AcidReceptors, N-Methyl-D-Aspartateaspartic acid receptorAutoantibodiesCarboplatinEtoposideReceptors, Amino AcidReceptors, N-Methyl-D-Aspartateanti-Hu antibodyanti-NMDAR antibodyautoimmune encephalitiscarboplatinetoposidesmall-cell lung cancer

Identifiers

PMID35768218
PMCPMC9970802
OpenAlexW4283762686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.