Evidence map›Paper›PMID 35768212›Full record

ArticleeNeuro

Lack of Causal Roles of Cannabinoid and Dopamine Neurotransmitter Systems in Orbitofrontal and Piriform Cortex in Fentanyl Relapse in Rats.

Sarah M Claypool, Sana Behdin, Sarah V Applebey, Javier Orihuel, Zilu Ma, David J Reiner

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sarah M ClaypoolIntramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224.
Sana BehdinIntramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224.
Sarah V ApplebeyIntramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224.
Javier OrihuelIntramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224.
Zilu MaIntramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224.
David J ReinerIntramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224 david.reiner@nih.gov.
National Institute on Drug Abuse · USNational Institutes of Health · US

Funding

STEM BUILD@UMBC: Student Training CoreTL4GM118989 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI LACOURSE, WILLIAM RICHARD · 2015 to 2023
$8.5M
NIDA-UMBC Research Training Pilot Year 2R25DA051338 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI William Richard LaCourse · 2020 to 2026
$1.1M
Role of glucagon-like peptide-1 in prescription opioid relapse and painFI2GM128603 · NIGMS · U.S. NATIONAL INSTITUTE ON DRUG ABUSE · PI REINER, DAVID · 2018 to 2018
–
NIDA NIH HHS R25 DA051338NIGMS NIH HHS FI2 GM128603NIGMS NIH HHS TL4 GM118989
6 · The paper itself

Abstract

The orbitofrontal cortex (OFC) and piriform cortex (Pir) play a role in fentanyl relapse after food choice-induced voluntary abstinence, a procedure mimicking abstinence because of availability of alternative nondrug rewards. We used

Indexed as

CannabinoidsPiriform CortexAnimalsDopamineDopamine AntagonistsFemaleFentanylMaleRatsReceptor, Cannabinoid, CB1Receptors, Dopamine D1RecurrenceCannabinoidsDopamineDopamine AntagonistsFentanylReceptor, Cannabinoid, CB1Receptors, Dopamine D1addictioncannabinoidsdopamineopioidrelapseself-administration

Identifiers

PMID35768212
PMCPMC9302236
OpenAlexW4283749274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.