Evidence map›Paper›PMID 35768104›Full record

ArticleBMJ open2022

Factors associated with cancer treatment delay: a protocol for a systematic review and meta-analysis.

Kristin E Morrill, Rogelio Robles-Morales, Melissa Lopez-Pentecost, Raigam J Martínez Portilla, Ahlam A Saleh, Meghan B Skiba, Taylor S Riall, Jessica D Austin, Rachel Hirschey, Elizabeth T Jacobs and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kristin E MorrillCommunity & Systems Health Science Division, The University of Arizona College of Nursing, Tucson, Arizona, USA morrill1@email.arizona.edu.ORCID 0000-0001-9970-4937
Rogelio Robles-MoralesDepartment of Clinical and Translational Sciences, The University of Arizona College of Medicine, Tucson, Arizona, USA.ORCID 0000-0002-8762-9455
Melissa Lopez-PentecostDepartment of Clinical and Translational Sciences, The University of Arizona College of Medicine, Tucson, Arizona, USA.ORCID 0000-0002-7048-3699
Raigam J Martínez PortillaIberoamerican Research Network in Obstetrics, Gynecology, and Translational Medicine, Mexico City, Mexico.
Ahlam A SalehHealth Sciences Library, The University of Arizona, Tucson, Arizona, USA.
Meghan B SkibaDivision of Biobehavioral Health Science, The University of Arizona College of Nursing, Tucson, Arizona, USA.ORCID 0000-0002-2244-5575
Taylor S RiallThe University of Arizona Cancer Center - North Campus, Tucson, Arizona, USA.
Jessica D AustinDepartment of Epidemiology, Mayo Clinic College of Medicine and Sciences, Scottsdale, Arizona, USA.ORCID 0000-0001-8286-7801
Rachel HirscheyUniversity of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, USA.
Elizabeth T JacobsThe University of Arizona Cancer Center - North Campus, Tucson, Arizona, USA.
Lena SpotlesonAmerican Cancer Society, Phoenix, Arizona, USA.
Timothy P HannaDepartment of Public Health Sciences, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0003-3228-6042

Funding

Cancer Prevention and Control Health Disparities Training ProgramT32CA078447 · NCI · UNIVERSITY OF ARIZONA · PI ALBERTS, DAVID SAMUEL, HARRIS, ROBIN B · 2016 to 2020
$1.2M
Sabor que Sana: Evaluation of a Traditional Mexican Dietary Pattern and NAFLD Risk in Mexican-origin Hispanic AdultsF31MD016283 · NIMHD · UNIVERSITY OF ARIZONA · PI PENTECOST, MELISSA LOPEZ · 2021 to 2022
$77k
NCI NIH HHS T32 CA078447NIMHD NIH HHS F31 MD016283
6 · The paper itself

Abstract

introductionTreatment delays are significantly associated with increased mortality risk among adult cancer patients; however, factors associated with these delays have not been robustly evaluated. This review and meta-analysis will evaluate factors associated with treatment delays among patients with five common cancers. METHODS AND ANALYSIS: Scientific databases including Ovid MEDLINE, Elsevier Embase, EBSCOhost CINAHL Plus Full Text, Elsevier Scopus and ProQuest Dissertations and Theses Global will be searched to identify relevant articles published between January 2000 and October 2021. Research articles published in the USA evaluating factors associated with treatment delay among breast, lung, prostate, cervical or colorectal adult cancer patients will be included. The primary outcome of the meta-analysis will be the pooled adjusted and unadjusted odds of treatment delay for patient, disease, provider and system-level factors defined according to specified time intervals. The secondary outcomes will be mean or median treatment delay for each cancer site according to first treatment and the influence of factors on the pooled mean treatment delay for each cancer site (via meta-regression analyses). Results from qualitative and mixed-methods studies will be narratively synthesised. Three reviewers will independently screen records generated from the search and two reviewers will independently extract data following a consensus agreement. Statistical heterogeneity will be assessed with a standard I ETHICS AND DISSEMINATION: Formal ethical approval is not required because the work is being carried out on publicly accessible studies. The findings of this review will be disseminated through a peer-reviewed scientific journal, academic conferences, social media, and key stakeholders. PROSPERO REGISTRATION NUMBER: CRD42021293131.

Indexed as

NeoplasmsTime-to-TreatmentAdultHumansMeta-Analysis as TopicResearch DesignReview Literature as TopicSystematic Reviews as Topicadult oncologyadult surgerychemotherapyquality in health careradiotherapy

Identifiers

PMID35768104
PMCPMC9240873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.