Evidence map›Paper›PMID 35768101›Full record

ArticleBMJ open2022

Whole-body photobiomodulation therapy for chronic pain: a protocol for a feasibility trial.

Bethany Fitzmaurice, Nicola R Heneghan, Asius Rayen, Andrew Soundy

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05069363 (Whole-Body Photobiomodulation Therapy for Chronic Pain), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05069363 narecruitingnot on this map

Whole-Body Photobiomodulation Therapy for Chronic Pain: a Feasibility Trial

TypeinterventionalSponsorSandwell & West Birmingham Hospitals NHS TrustRan2022 to 2023Enrolled20ConditionsChronic PainArmsWhole-Body Photobiomodulation Therapy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bethany FitzmauriceSchool of Sport Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK bfitzmaurice@nhs.net.ORCID 0000-0001-7365-4177
Nicola R HeneghanSchool of Sport Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0001-7599-3674
Asius RayenDepartment of Pain Management, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
Andrew SoundySchool of Sport Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0002-5118-5872
Sandwell & West Birmingham Hospitals NHS Trust · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic pain conditions are a leading cause of disease and disability. They are associated with symptoms such as fatigue, sleep and mood disturbances. Minimal evidence is available to support effective treatments and alternatives treatment approaches are called for. Photobiomodulation therapy has been highlighted as one promising option. A whole-body therapy device (NovoTHOR) has recently been developed with a number of potential advantages for people with chronic pain. Research is needed to consider the feasibility of this device. METHODS AND ANALYSIS: A single-centre single-armed (no placebo group) feasibility study with an embedded qualitative component will be conducted. The intervention will comprise 18 treatments over 6 weeks, with 6-month follow-up, in the whole-body photobiomodulation device. A non-probability sample of 20 adult participants with a clinician diagnosis of chronic axial pain, polyarthralgia, myofascial pain or widespread pain will be recruited (self-referral and clinician referral). Outcome measures will focus on acceptability of trial processes with a view to guiding a definitive randomised controlled trial. Analyses will use descriptive statistics for quantitative aspects. The qualitative element will be assessed by means of a participant-reported experience questionnaire postintervention and semistructured audio-recorded interviews at three stages; preintervention, midintervention and postintervention. The latter will be transcribed verbatim and a reflexive thematic analysis will be used to identify emerging themes. Exploratory outcomes (participant-reported and performance-based measures) will be analysed according to data distribution. ETHICS AND DISSEMINATION: The study has received ethical approval from the Leicester Central Research and Ethics Committee. Findings will be disseminated via local chronic pain groups, public register update, submission for presentation at scientific meetings and open-access peer-reviewed journals, and via academic social networks. TRIAL REGISTRATION NUMBER: NCT05069363.

Indexed as

Chronic PainLow-Level Light TherapyAdultChronic DiseaseFeasibility StudiesHumansPain MeasurementRandomized Controlled Trials as Topicmusculoskeletal disorderspain managementrheumatology

Identifiers

PMID35768101
PMCPMC9244683
OpenAlexW4283745109

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.