Evidence map›Paper›PMID 35768100›Full record

ArticleBMJ open2022

Global burden of musculoskeletal disorders and attributable factors in 204 countries and territories: a secondary analysis of the Global Burden of Disease 2019 study.

Shiwen Liu, Binyan Wang, Shuzhen Fan, Yaxuan Wang, Yuxuan Zhan, Ding Ye

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06747052 (Gender Impact On Physical Activity In Chronic Musculoskeletal Disorders Prevention), which is not on this map. Cited by 142 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 12 pooled it
63.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06747052 recruitingnot on this mapstarted 2025, after this paper: background citation

Gender Impact On Physical Activity In Chronic Musculoskeletal Disorders Prevention: A Survey-based Cross-sectional Study in Regione Lombardia

TypeobservationalSponsorI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioRan2025 to 2026Enrolled1,310ConditionsPhysical Activity, Musculoskeletal Disease, Gender Equity
3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 12 syntheses or guidelines pooled it, 247 citations in OpenAlex.

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  7. Work-Related Musculoskeletal Disorders in Endoscopic Sinus and Skull Base Surgery: A Systematic Review With Meta-analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
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  9. Mobile technologies for rehabilitation in non-specific spinal disorders: a systematic review of the efficacy and potential for implementation in low- and middle-income countries.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shiwen Liu *School of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.
Binyan Wang *School of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.
Shuzhen FanSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.
Yaxuan WangSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.
Yuxuan ZhanSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.
Ding YeSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou, China yeding@zcmu.edu.cn.ORCID 0000-0001-6654-7832
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the global burden of musculoskeletal (MSK) disorders, as well as the five common conditions, and their relevant risk factors from 1990 to 2019.

designData from the Global Burden of Disease Study 2019 were used in this study. SETTING AND

participantsIndividuals of all ages and genders from 204 countries and territories in 21 regions.

main outcome measuresThe outcomes were the numbers and age-standardised rates (ASRs) of incident cases, deaths and disability-adjusted life-years (DALYs) of MSK disorders. The average annual percent changes (AAPCs) in the ASRs were calculated using joinpoint regression analysis to estimate the trends.

resultsThere were 322.75 million incident cases, 117.54 thousand deaths and 150.08 million DALYs of MSK disorders in 2019. The age-standardised incidence rate and age-standardised DALY rate in 2019 (incidence: AAPC=-0.32, 95% CI -0.34 to -0.31; DALYs: AAPC=-0.05, 95% CI -0.06 to -0.04) were lower than those in 1990. However, the age-standardised death rate showed a stable trend (AAPC 0.05, 95% CI -0.05 to 0.15) from 1990 to 2019. The peak age of onset and DALYs of MSK disorders was 50-54 years in 2019. The burden of MSK disorders in females was much higher than that in males (1.29 times more incident cases, 2.24 times more deaths and 1.45 times more DALYs in females than in males). A significant negative correlation was observed between the AAPCs in the ASRs and the Sociodemographic Index (SDI) score. Occupational risk exhibited the highest contribution to MSK disorders, and tobacco use and high body mass index were also major risk factors.

conclusionsThis study demonstrates that the burden of MSK disorders tends to be lower in high-SDI regions than in lower-SDI regions. Strengthening the effectiveness of preventive measures against occupational risks may reduce the burden of MSK disorders.

Indexed as

Global Burden of DiseaseMusculoskeletal DiseasesBody Mass IndexFemaleGlobal HealthHumansMaleMiddle AgedQuality-Adjusted Life YearsRisk Factorsepidemiologymusculoskeletal disorderspublic health

Identifiers

PMID35768100
PMCPMC9244680
OpenAlexW4283753489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.