ArticleCurrent biology : CB2022
Selective enhancement of neural coding in V1 underlies fine-discrimination learning in tree shrew.
Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- How perceptual learning rewires brain connectivity: lessons from the visual system in a top-down perspective.Frontiers in neural circuits · 2025Pooled it
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- Visual Motion Processing in The Tree Shrew Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Mapping function in the tree shrew visual system using functional ultrasound imaging.bioRxiv : the preprint server for biology · 2025Article
- Article
- High-throughput markerless pose estimation and home-cage activity analysis of tree shrew using deep learning.Animal models and experimental medicine · 2025Article
- A Global Survey on the Perception of Conservationists Regarding Animal Consciousness.Animals : an open access journal from MDPI · 2025Article
- Article
- Unexpected Retinal Abnormalities in the Cone-Dominant Northern Tree Shrew.Advances in experimental medicine and biology · 2025Article
- Cognitive Deficits and Alzheimer's Disease-Like Pathologies in the Aged Chinese Tree Shrew.Molecular neurobiology · 2024Article
- Profiles of visual perceptual learning in feature space.iScience · 2024Article
- Cellular Characterization and Interspecies Evolution of the Tree Shrew Retina across Postnatal Lifespan.Research (Washington, D.C.) · 2024Article
- Article
- A comparison of behavioral paradigms assessing spatial memory in tree shrews.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Neural circuits for binocular vision: Ocular dominance, interocular matching, and disparity selectivity.Frontiers in neural circuits · 2023Review
- Strong tuning for stereoscopic depth indicates orientation-specific recurrent circuitry in tree shrew V1.Current biology : CB · 2022Article
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4 authors at 1 institution in 1 country.
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Abstract
Visual discrimination improves with training, a phenomenon that is thought to reflect plastic changes in the responses of neurons in primary visual cortex (V1). However, the identity of the neurons that undergo change, the nature of the changes, and the consequences of these changes for other visual behaviors remain unclear. We used chronic in vivo 2-photon calcium imaging to monitor the responses of neurons in the V1 of tree shrews learning a Go/No-Go fine orientation discrimination task. We observed increases in neural population measures of discriminability for task-relevant stimuli that correlate with performance and depend on a select subset of neurons with preferred orientations that include the rewarded stimulus and nearby orientations biased away from the non-rewarded stimulus. Learning is accompanied by selective enhancement in the response of these neurons to the rewarded stimulus that further increases their ability to discriminate the task stimuli. These changes persist outside of the trained task and predict observed enhancement and impairment in performance of other discriminations, providing evidence for selective and persistent learning-induced plasticity in the V1, with significant consequences for perception.
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