Evidence map›Paper›PMID 35767773›Full record

ArticleNeurocase2022

Pupillometry as an index for cognitive processing in behavioral variant FrontoTemporal Dementia: a series of case studies.

Mohamad El Haj, Dimitrios Kapogiannis, Claire Boutoleau-Bretonnière

Open access · greenAbstract read
In one paragraph

Article in Neurocase, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Mohamad El HajLaboratoire de psychologie des Pays de la Loire, Nantes Université, Univ Angers, LPPL, Nantes, France.ORCID 0000-0001-7635-7557
Dimitrios KapogiannisLaboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, USA.
Claire Boutoleau-BretonnièreDépartement de Neurologie, CHU Angers, Angers, France.
Inserm · FRInstitut Universitaire de France · FRNational Institute on Aging · US

Funding

Studies in Dementia and Neurodegenerative DiseasesZIAAG000975 · NIA · NATIONAL INSTITUTE ON AGING · PI KAPOGIANNIS, DIMITRIOS · 2009 to 2025
$31.5M
Intramural NIH HHS Z99 AG999999Intramural NIH HHS ZIA AG000975
6 · The paper itself

Abstract

We investigated whether pupil size can variate with the intensity of cognitive processing in patients with behavioral-variant-Frontotemporal-Dementia (bvFTD). We invited five bvFTD participants and 21 controls to perform forward spans and backward spans, and, in a control condition, to count aloud. We recorded pupil activity using eye-tracking-glasses during the spans and control condition. Analysis demonstrated larger pupil sizes during backward spans than during forward spans, and larger pupil sizes during forward spans than during counting in both bvFTD and control participants. These findings demonstrate how increased cognitive load triggers increased pupil size and how this connection is maintained in bvFTD.

Indexed as

Alzheimer DiseaseFrontotemporal DementiaCognitionHumansNeuropsychological TestsBehavioral variant FrontoTemporal Dementiacognitive loadFrontoTemporal Dementiapupillometryspans

Identifiers

PMID35767773
PMCPMC9474719
OpenAlexW4283707148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.