Evidence map›Paper›PMID 35767663›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis.

Relber A Gonçales, Helder Novais Bastos, Cláudio Duarte-Oliveira, Daniela Antunes, Oksana Sokhatska, Maria Jacob, Rui Rolo, Cláudia F Campos, Sergio D Sasaki, Alessia Donato and 14 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. The Renin-Angiotensin-Aldosterone System Regulates Sarcoidosis Granulomatous Inflammation.American journal of respiratory and critical care medicine · 2024
    Article
  7. Article
  8. Common Clinical and Molecular Pathways between Migraine and Sarcoidosis.International journal of molecular sciences · 2023
    Review
  9. Humoral Innate Immunity and Acute-Phase Proteins.The New England journal of medicine · 2023
    Review
  10. PTX3 in Granuloma Formation and Sarcoidosis: Helping Macrophages Accept a "Complement".American journal of respiratory and critical care medicine · 2022
    Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 10 institutions in 7 countries.

Relber A GonçalesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Helder Novais Bastosi3S - Instituto de Investigação e Inovação em Saúde.
Cláudio Duarte-OliveiraLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Daniela AntunesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Oksana SokhatskaBasic and Clinical Immunology, Department of Pathology, Faculty of Medicine, and.
Maria JacobDepartment of Pneumology and.
Rui RoloDepartment of Pneumology, Hospital de Braga, Braga, Portugal.
Cláudia F CamposLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Sergio D SasakiLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Alessia DonatoIRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Sarah N MapelliIRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Sandra CostaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Conceição Souto MouraDepartment of Pathology, Centro Hospitalar Universitário de São João, Porto, Portugal.
Luís DelgadoBasic and Clinical Immunology, Department of Pathology, Faculty of Medicine, and.
António MoraisDepartment of Pneumology and.
Egídio TorradoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Frank L van de VeerdonkDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.ORCID 0000-0002-1121-4894
Thomas WeichhartCenter of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
John D LambrisDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and.
Ricardo SilvestreLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Cecilia GarlandaIRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Alberto MantovaniIRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Cristina CunhaLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.ORCID 0000-0002-6002-5782
Agostinho CarvalhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.ORCID 0000-0001-8935-8030
University of Minho · PTHumanitas University · ITHospital Braga · PTHospital de São João · PTi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTMedical University of Vienna · ATRadboud University Nijmegen · NLUniversidade do Porto · PTUniversidade Federal do ABC · BRUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

C-Reactive ProteinMacrophage ActivationSarcoidosisSerum Amyloid P-ComponentAnimalsComplement System ProteinsGranulomaHumansInflammationLeukocytes, MononuclearMicePentraxinsComplement System ProteinsC-Reactive ProteinPentraxinsSerum Amyloid P-Componentcomplement system proteinsgranulomahumoral immunitymacrophagessarcoidosis

Identifiers

PMID35767663
PMCPMC9704840
OpenAlexW4283765100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.