Evidence map›Paper›PMID 35767430›Full record

ArticleJournal of the American Geriatrics Society2022

Dementia prevalence, a contextual factor associated with SARS-CoV-2 in veterans affairs community living centers.

Thomas A Bayer, Frank DeVone, Kevin W McConeghy, Christopher W Halladay, Lien Quach, Ashna Rajan, Salaheldin Elhamamsy, Marilyne Cadieux, Mriganka Singh, Moniyka Sachar and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Epidemiology and Clinical Presentation of COVID-19 in Older Adults.Infectious disease clinics of North America · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Thomas A BayerCenter of Innovation, Long-Term Services and Support, Providence Veterans Administration Medical Center, Providence, Rhode Island, USA.
Frank DeVoneCenter of Innovation, Long-Term Services and Support, Providence Veterans Administration Medical Center, Providence, Rhode Island, USA.
Kevin W McConeghyCenter of Innovation, Long-Term Services and Support, Providence Veterans Administration Medical Center, Providence, Rhode Island, USA.
Christopher W HalladayCenter of Innovation, Long-Term Services and Support, Providence Veterans Administration Medical Center, Providence, Rhode Island, USA.
Lien QuachDepartment of Gerontology, University of Massachusetts Boston, Boston, Massachusetts, USA.
Ashna RajanDivision of Geriatrics and Palliative Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Salaheldin ElhamamsyDivision of Geriatrics and Palliative Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Marilyne CadieuxDivision of Geriatrics and Palliative Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Mriganka SinghCenter of Innovation, Long-Term Services and Support, Providence Veterans Administration Medical Center, Providence, Rhode Island, USA.
Moniyka SacharDivision of Geriatrics and Palliative Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Aman NandaDivision of Geriatrics and Palliative Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Stefan GravensteinCenter of Innovation, Long-Term Services and Support, Providence Veterans Administration Medical Center, Providence, Rhode Island, USA.
James L RudolphCenter of Innovation, Long-Term Services and Support, Providence Veterans Administration Medical Center, Providence, Rhode Island, USA.
Brown University · USProvidence VA Medical Center · USUniversity of Massachusetts Boston · US

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI · 2007 to 2026
$38.9M
HSRD VA C19 20-213NIA NIH HHS P01 AG027296
6 · The paper itself

Abstract

backgroundAlzheimer's disease and related dementias (ADRD) impact the diagnosis and infection control of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in nursing homes (NH) by influencing the behavior of residents and their caregivers. Health system data show an association between ADRD and SARS-CoV-2. Whether this association is present in NH populations remains unknown. How increased SARS-CoV-2 risk among residents with ADRD impacts the greater NH population also remains unknown.

methodsThis retrospective cohort study used electronic health record data on Veterans residing in 133 Veterans Affairs Community Living Centers (CLC) and 15 spinal cord injury units from March 1, 2020 to December 13, 2020. We measured ADRD using diagnostic codes 12 months before an index SARS-CoV-2 test date for each resident. We used Poisson regression to determine the relative risk of SARS-CoV-2 for the highest quartile of facility ADRD prevalence versus the lowest, stratifying by individual ADRD status, and adjusting for covariates, with and without a random intercept to account for facility clustering.

resultsAcross the study period, 15,043 residents resided in CLCs, 1952 (13.0%) had SARS-CoV-2, and 8067 (53.6%) had ADRD. There was an estimated 60% increased risk of SARS-CoV-2 in facilities with highest dementia prevalence versus lowest (relative risk, 1.6 [95% confidence interval 0.95, 2.7]).

conclusionsCLC residents had a greater likelihood of SARS-CoV-2 infection in facilities with greater ADRD prevalence. Facility characteristics other than ADRD prevalence may account for this association.

Indexed as

Alzheimer DiseaseCOVID-19VeteransHumansPrevalenceRetrospective StudiesSARS-CoV-2dementianursing homeSARS-CoV-2

Identifiers

PMID35767430
PMCPMC9349562
OpenAlexW4283719683

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.