ArticleTranslational vision science & technology2022
Comparison of Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer Thickness Values Using Spectral-Domain and Swept-Source OCT.
Article in Translational vision science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Comparison of Macular Ganglion Cell-Inner Plexiform Layer Thickness and Sectoral Ratio Asymmetry Among Different Glaucoma Types.Diagnostics (Basel, Switzerland) · 2026Article
- Predicting HFA 30-2 Visual Fields with Deep Learning from Multimodal OCT-Fundus Feature Fusion and Structure-Function Discordance Analysis.Journal of imaging informatics in medicine · 2026Article
- Anterior ischemic optic neuropathy in patients treated with semaglutide: report of four cases with a possible association.BMC ophthalmology · 2025Article
- Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes.Frontiers in medicine · 2025Article
- Effect of latanoprost on choroidal thickness in patients with newly diagnosed primary open-angle glaucoma.Northern clinics of Istanbul · 2024Article
- Agreement, repeatability, and reproducibility of quantitative retinal layer assessment using swept-source and spectral-domain optical coherence tomography in eyes with retinal diseases.Frontiers in medicine · 2023Article
- Evaluation of optical coherence tomography in patients with coronary artery disease and systemic hypertension.Oman journal of ophthalmologyArticle
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To compare peripapillary retinal nerve fiber layer (pRNFL) and macular ganglion cell-inner plexiform layer (mGCIPL) thickness measurements obtained with spectral domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT) using an OCT-angiography scanning protocol, and their ability to distinguish among patients with glaucoma, glaucoma suspects (GS), and healthy controls (HC). Methods: Cross-sectional study of 196 eyes (81 glaucoma, 48 GS, and 67 HC) of 119 participants. Participants underwent peripapillary and macular OCT with SD-OCT and SS-OCT. Parameters of interest were average and sector-wise pRNFL and mGCIPL thickness. Inter-device agreement was investigated with Bland-Altman statistics. Conversion formulas were developed with linear regression. Diagnostic performances were evaluated with area under the receiver operating characteristic curves. Results: Both SD-OCT and SS-OCT detected a significant pRNFL and mGCIPL thinning in glaucoma patients compared to HC and GS for almost all study sectors. A strong linear relationship between the two devices was present for all quadrants/sectors (R2 ≥ 0.81, P < 0.001), except for the nasal (R2 = 0.49, P < 0.001) and temporal (R2 = 0.62, P < 0.001) pRNFL quadrants. SD-OCT and SS-OCT measurements had a proportional bias, which could be removed with conversion formulas. Overall, the two devices showed similar diagnostic abilities. Conclusions: Thickness values obtained with SD-OCT and SS-OCT are not directly interchangeable but potentially interconvertible. Both devices have a similar ability to discriminate glaucoma patients from GS and healthy subjects. Translational Relevance: OCT-Angiography scans can be reliably used to obtain structural metrics in glaucoma patients.
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